Journal article
Molecular subgroups of atypical teratoid rhabdoid tumours in children: an integrated genomic and clinicopathological analysis
Abstract
BACKGROUND: Rhabdoid brain tumours, also called atypical teratoid rhabdoid tumours, are lethal childhood cancers with characteristic genetic alterations of SMARCB1/hSNF5. Lack of biological understanding of the substantial clinical heterogeneity of these tumours restricts therapeutic advances. We integrated genomic and clinicopathological analyses of a cohort of patients with atypical teratoid rhabdoid tumours to find out the molecular basis …
Authors
Torchia J; Picard D; Lafay-Cousin L; Hawkins CE; Kim S-K; Letourneau L; Ra Y-S; Ho C; Chan TSY; Sin-Chan P
Journal
The Lancet Oncology, Vol. 16, No. 5, pp. 569–582
Publisher
Elsevier
Publication Date
May 2015
DOI
10.1016/s1470-2045(15)70114-2
ISSN
1470-2045