Evidence for neuronal expression of functional Fc (ε and γ) receptors Journal Articles

abstract

• We report that neurons express functional Fc receptors (including FcεR1), that can be activated by antigen, transmit signals along nerve fibers in vitro and in vivo. These results open new avenues of investigation in neurogenic inflammation and allergic diseases.

authors

• van der Kleij, Hanneke
• Charles, Nicolas
• Karimi, Khalil
• Mao, Yu-Kang
• Foster, Jane
• Janssen, Luke Jeffrey
• Chang Yang, Ping
• Kunze, Wolfgang
• Rivera, Juan
• Bienenstock, John

status

• published 

publication date

• March 2010

has subject area

• 1107 Immunology (FoR)
• Allergy (Science Metrix)
• Animals (MeSH)
• Cell Communication (MeSH)
• Mice (MeSH)
• Neurons (MeSH)
• RNA, Messenger (MeSH)
• Receptors, IgE (MeSH)
• Receptors, IgG (MeSH)
• Reverse Transcriptase Polymerase Chain Reaction (MeSH)
• Signal Transduction (MeSH)

published in

• Journal of Allergy and Clinical Immunology  Journal

keywords

• Animals
• Cell Communication
• Mice
• Neurons
• RNA, Messenger
• Receptors, IgE
• Receptors, IgG
• Reverse Transcriptase Polymerase Chain Reaction
• Signal Transduction

Digital Object Identifier (DOI)

• 10.1016/j.jaci.2009.10.054

start page

• 757

end page

• 760

volume

• 125

issue

• 3