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Vasopressin increases intracellular NO...
Journal article

Vasopressin increases intracellular NO concentration via Ca(2+) signaling in inner medullary collecting duct.

Abstract

The present study was designed to determine whether arginine vasopressin (AVP) stimulates NO production in the epithelial collecting duct cells of the inner medulla (IMCDs) and if this is mediated through Ca(2+) signaling. Thin tissue layers containing IMCDs were dissected from Sprague-Dawley rats. Intracellular Ca(2+) concentration ([Ca(2+)](i)) and NO production were measured in IMCDs by a fluorescence imaging system with the use of fura 2-AM …

Authors

Mori T; Dickhout JG; Cowley AW

Journal

Hypertension, Vol. 39, No. 2 Pt 2, pp. 465–469

Publication Date

2 2002

DOI

10.1161/hy02t2.102908