Journal article
Mechanisms associated with mitochondrial-generated reactive oxygen species in cancerThis article is one of a selection of papers published in a Special Issue on Oxidative Stress in Health and Disease.
Abstract
The mitochondria are unique cellular organelles that contain their own genome and, in conjunction with the nucleus, are able to transcribe and translate genes encoding components of the electron transport chain (ETC). To do so, the mitochondria must communicate with the nucleus via the production of reactive oxygen species (ROS) such as hydrogen peroxide (H2O2), which are produced as a byproduct of aerobic respiration within the mitochondria. …
Authors
Verschoor ML; Wilson LA; Singh G
Journal
Canadian Journal of Physiology and Pharmacology, Vol. 88, No. 3, pp. 204–219
Publisher
Canadian Science Publishing
Publication Date
3 2010
DOI
10.1139/y09-135
ISSN
0008-4212