Journal article
Signal Transduction Pathways Involved in Enterohemorrhagic Escherichia coli-Induced Alterations in T84 Epithelial Permeability
Abstract
Enterohemorrhagic Escherichia coli (EHEC) infection is associated with watery diarrhea and can lead to complications, including hemorrhagic colitis and the hemolytic-uremic syndrome. The mechanisms by which these organisms produce diarrheal disease remain to be elucidated. Changes in T84 epithelial cell electrophysiology were examined following EHEC infection. T84 cell monolayers infected with EHEC O157:H7 displayed a time-dependent decrease in …
Authors
Philpott DJ; McKay DM; Mak W; Perdue MH; Sherman PM
Journal
Infection and Immunity, Vol. 66, No. 4, pp. 1680–1687
Publisher
American Society for Microbiology
Publication Date
April 1998
DOI
10.1128/iai.66.4.1680-1687.1998
ISSN
0019-9567