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Cells Exposed to Sublethal Oxidative Stress...
Journal article

Cells Exposed to Sublethal Oxidative Stress Selectively Attract Monocytes/Macrophages via Scavenger Receptors and MyD88-Mediated Signaling

Abstract

The innate immune system responds to endogenous molecules released during cellular stress or those that have undergone modifications normally absent in healthy tissue. These structures are detected by pattern-recognition receptors, alerting the immune system to "danger." In this study, we looked for early signals that direct immune cells to cells undergoing stress before irreversible damage takes place. To avoid detecting signals emanating from …

Authors

Geiger-Maor A; Levi I; Even-Ram S; Smith Y; Bowdish DM; Nussbaum G; Rachmilewitz J

Journal

The Journal of Immunology, Vol. 188, No. 3, pp. 1234–1244

Publisher

Oxford University Press (OUP)

Publication Date

February 1, 2012

DOI

10.4049/jimmunol.1101740

ISSN

0022-1767