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Bystander-induced differentiation: A major...
Journal article

Bystander-induced differentiation: A major response to targeted irradiation of a urothelial explant model

Abstract

A ureter primary explant technique, using porcine tissue sections was developed to study bystander effects under in vivo like conditions where dividing and differentiated cells are present. Targeted irradiations of ureter tissue fragments were performed with the Gray Cancer Institute charged particle microbeam at a single location (2 microm precision) with 10 3He2+ particles (5 MeV; LET 70 keV/microm). After irradiation the ureter tissue …

Authors

Belyakov OV; Folkard M; Mothersill C; Prise KM; Michael BD

Journal

Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis, Vol. 597, No. 1-2, pp. 43–49

Publisher

Elsevier

Publication Date

5 2006

DOI

10.1016/j.mrfmmm.2005.08.012

ISSN

0027-5107