Journal article
β-Catenin/Smad3 Interaction Regulates Transforming Growth Factor-β-Induced Epithelial to Mesenchymal Transition in the Lens
Abstract
Cataracts are the leading cause of blindness worldwide. Although surgery is a successful method to restore vision loss due to cataracts, post-surgical complications can occur, such as secondary cataracts, also known as posterior capsular opacification (PCO). PCO arises when lens epithelial cells (LEC) are left behind in the capsular bag following surgery and are induced to undergo epithelial to mesenchymal transition (EMT). Following EMT, LEC …
Authors
Taiyab A; Holms J; West-Mays JA
Journal
International Journal of Molecular Sciences, Vol. 20, No. 9,
Publisher
MDPI
DOI
10.3390/ijms20092078
ISSN
1661-6596