Journal article
AHR signaling is induced by infection with coronaviruses
Abstract
Coronavirus infection in humans is usually associated to respiratory tract illnesses, ranging in severity from mild to life-threatening respiratory failure. The aryl hydrocarbon receptor (AHR) was recently identified as a host factor for Zika and dengue viruses; AHR antagonists boost antiviral immunity, decrease viral titers and ameliorate Zika-induced pathology in vivo. Here we report that AHR is activated by infection with different …
Authors
Giovannoni F; Li Z; Remes-Lenicov F; Dávola ME; Elizalde M; Paletta A; Ashkar AA; Mossman KL; Dugour AV; Figueroa JM
Journal
Nature Communications, Vol. 12, No. 1,
Publisher
Springer Nature
DOI
10.1038/s41467-021-25412-x
ISSN
2041-1723