Polymorphism, Single Nucleotide Concept

subject area of

• 16p11.2 600 kb Duplications confer risk for typical and atypical Rolandic epilepsy.  Academic Article
• A Family Based Study of Carbon Monoxide and Nitric Oxide Signalling Genes and Preeclampsia.  Academic Article
• A Genome-Wide Association Study to Identify Single-Nucleotide Polymorphisms for Acute Kidney Injury.  Academic Article
• A Genome-wide Association Study Identifies Risk Alleles in Plasminogen and P4HA2 Associated with Giant Cell Arteritis.  Academic Article
• A discovery resource of rare copy number variations in individuals with autism spectrum disorder.  Academic Article
• A fast algorithm to optimize SNP prioritization for gene-gene and gene-environment interactions.  Academic Article
• A gene variant in CERS2 is associated with rate of increase in albuminuria in patients with diabetes from ONTARGET and TRANSCEND.  Academic Article
• A genetic link between prepregnancy body mass index, postpartum weight retention, and offspring weight in early childhood.  Academic Article
• A genetic study of the ghrelin and growth hormone secretagogue receptor (GHSR) genes and stature.  Academic Article
• A genome-wide association meta-analysis identifies new childhood obesity loci.  Academic Article
• A genome-wide association search for type 2 diabetes genes in African Americans.  Academic Article
• A genome-wide association study for coronary artery disease identifies a novel susceptibility locus in the major histocompatibility complex.  Academic Article
• A genome-wide association study for venous thromboembolism: the extended cohorts for heart and aging research in genomic epidemiology (CHARGE) consortium.  Academic Article
• A genome-wide association study identifies rs2000999 as a strong genetic determinant of circulating haptoglobin levels.  Academic Article
• A genome-wide scan for common alleles affecting risk for autism.  Academic Article
• A high-throughput sequencing test for diagnosing inherited bleeding, thrombotic, and platelet disorders.  Academic Article
• A large-scale candidate gene association study of age at menarche and age at natural menopause.  Academic Article
• A method to estimate the contribution of regional genetic associations to complex traits from summary association statistics.  Academic Article
• A novel approach of homozygous haplotype sharing identifies candidate genes in autism spectrum disorder.  Academic Article
• A novel large deletion and three polymorphisms in the FECH gene associated with erythropoietic protoporphyria.  Academic Article
• A pharmacogenetic analysis of the Canadian Cancer Trials Group MY.10 clinical trial of maintenance therapy for multiple myeloma.  Academic Article
• A polymorphism within the G6PC2 gene is associated with fasting plasma glucose levels.  Academic Article
• A preliminary analysis of the DNA and diet of the extinct Beothuk: a systematic approach to ancient human DNA.  Academic Article
• A preliminary pharmacogenetic investigation of adverse events from topiramate in heavy drinkers.  Academic Article
• A principal component regression based genome wide analysis approach reveals the presence of a novel QTL on BTA7 for MAP resistance in holstein cattle.  Academic Article
• A rare variant in the visfatin gene (NAMPT/PBEF1) is associated with protection from obesity.  Academic Article
• A review of the associations between single nucleotide polymorphisms in taste receptors, eating behaviors, and health.  Academic Article
• A transforming growth factorbeta1 signal peptide variant increases secretion in vitro and is associated with increased incidence of invasive breast cancer.  Academic Article
• A variant near MTNR1B is associated with increased fasting plasma glucose levels and type 2 diabetes risk.  Academic Article
• ACDC/adiponectin polymorphisms are associated with severe childhood and adult obesity.  Academic Article
• APOA5 and APOA1 polymorphisms are associated with triglyceride levels in Mexican children.  Academic Article
• APOA5 genetic variants are markers for classic hyperlipoproteinemia phenotypes and hypertriglyceridemia.  Academic Article
• Adiponectin, type 2 diabetes and the metabolic syndrome: lessons from human genetic studies.  Academic Article
• An evaluation of logic regression-based biomarker discovery across multiple intergenic regions for predicting host specificity in Escherichia coli.  Academic Article
• An initial investigation of associations between dopamine-linked genetic variation and smoking motives in African Americans.  Academic Article
• Analysis of novel risk loci for type 2 diabetes in a general French population: the D.E.S.I.R. study.  Academic Article
• Analysis of the SIM1 contribution to polygenic obesity in the French population.  Academic Article
• Analysis of the contribution of FTO, NPC1, ENPP1, NEGR1, GNPDA2 and MC4R genes to obesity in Mexican children.  Academic Article
• Assessing host-specificity of Escherichia coli using a supervised learning logic-regression-based analysis of single nucleotide polymorphisms in intergenic regions.  Academic Article
• Assessing the effects of 35 European-derived BMI-associated SNPs in Mexican children.  Academic Article
• Association analyses of 249,796 individuals reveal 18 new loci associated with body mass index.  Academic Article
• Association analysis indicates that a variant GATA-binding site in the PIK3CB promoter is a Cis-acting expression quantitative trait locus for this gene and attenuates insulin resistance in obese children.  Academic Article
• Association between C reactive protein and coronary heart disease: mendelian randomisation analysis based on individual participant data.  Academic Article
• Association between a literature-based genetic risk score and cardiovascular events in women.  Academic Article
• Association between alcohol and cardiovascular disease: Mendelian randomisation analysis based on individual participant data.  Academic Article
• Association between phosphodiesterase 4D gene and ischaemic stroke.  Academic Article
• Association between the FTO rs9939609 polymorphism and the metabolic syndrome in a non-Caucasian multi-ethnic sample.  Academic Article
• Association between tumor necrosis factor-alpha promoter -308 A/G polymorphism and susceptibility to sepsis and sepsis mortality: a systematic review and meta-analysis.  Academic Article
• Association of COX-2 gene haplotypes with prostaglandins production in bronchial asthma.  Academic Article
• Association of TLR4 polymorphisms with Mycobacterium avium subspecies paratuberculosis infection status in Canadian Holsteins.  Academic Article
• Association of a functional variant in the Wnt co-receptor LRP6 with early onset ileal Crohn's disease.  Academic Article
• Association of common variants in the human eyes shut ortholog (EYS) with statin-induced myopathy: evidence for additional functions of EYS.  Academic Article
• Association of granulomatosis with polyangiitis (Wegener's) with HLA-DPB1*04 and SEMA6A gene variants: evidence from genome-wide analysis.  Academic Article
• Association of melanin-concentrating hormone receptor 1 5' polymorphism with early-onset extreme obesity.  Academic Article
• Association of renin-angiotensin and endothelial nitric oxide synthase gene polymorphisms with blood pressure progression and incident hypertension: prospective cohort study.  Academic Article
• Association of the macrophage migration inhibitory factor -173G/C polymorphism with Chagas disease.  Academic Article
• Association of variation at the ABO locus with circulating levels of soluble intercellular adhesion molecule-1, soluble P-selectin, and soluble E-selectin: a meta-analysis.  Academic Article
• Association studies on ghrelin and ghrelin receptor gene polymorphisms with obesity.  Academic Article
• Association study of tryptophan hydroxylase 2 gene polymorphisms in bipolar disorder patients with panic disorder comorbidity.  Academic Article
• Associations between parenting behavior and anxiety in a rodent model and a clinical sample: relationship to peripheral BDNF levels.  Academic Article
• Associations of the FTO rs9939609 variant with discrete body fat depots and dietary intake in a multi-ethnic cohort.  Academic Article
• BDNF Val66Met polymorphism and peripheral protein levels in pediatric bipolar disorder and attention-deficit/hyperactivity disorder.  Academic Article
• BRCA2 variants and cardiovascular disease in a multi-ethnic study.  Academic Article
• Bardet-Biedl syndrome gene variants are associated with both childhood and adult common obesity in French Caucasians.  Academic Article
• Bioinformatic analyses identifies novel protein-coding pharmacogenomic markers associated with paclitaxel sensitivity in NCI60 cancer cell lines.  Academic Article
• Biological, clinical and population relevance of 95 loci for blood lipids.  Academic Article
• Birth weight interacts with a functional variant of the oxytocin receptor gene (OXTR) to predict executive functioning in children.  Academic Article
• Bovine CLEC7A genetic variants and their association with seropositivity in Johne's disease ELISA.  Academic Article
• Bovine IFNGR2, IL12RB1, IL12RB2, and IL23R polymorphisms and MAP infection status.  Academic Article
• Bovine PGLYRP1 polymorphisms and their association with resistance to Mycobacterium avium ssp. paratuberculosis.  Academic Article
• Brain-derived neurotrophic factor gene val66met polymorphism and executive functioning in patients with bipolar disorder.  Academic Article
• COL4A2 is associated with lacunar ischemic stroke and deep ICH: Meta-analyses among 21,500 cases and 40,600 controls.  Academic Article
• CYP7A1, BAAT and UGT1A1 polymorphisms and susceptibility to anti-tuberculosis drug-induced hepatotoxicity.  Academic Article
• Causal relationship between adiponectin and metabolic traits: a Mendelian randomization study in a multiethnic population.  Academic Article
• Causal relationship between obesity and vitamin D status: bi-directional Mendelian randomization analysis of multiple cohorts.  Academic Article
• Causes and consequences of genetic background effects illuminated by integrative genomic analysis.  Academic Article
• Centrotemporal sharp wave EEG trait in rolandic epilepsy maps to Elongator Protein Complex 4 (ELP4).  Academic Article
• Cervical artery dissection: pathology, epidemiology and management.  Academic Article
• Childhood gene-environment interactions and age-dependent effects of genetic variants associated with refractive error and myopia: The CREAM Consortium.  Academic Article
• Clinical and molecular delineation of the 17q21.31 microdeletion syndrome.  Academic Article
• Clinical evaluation of a hemochromatosis next-generation sequencing gene panel.  Academic Article
• Clinical, biochemical, and genetic predictors of coronary artery bypass graft failure.  Academic Article
• Collagen platelet receptor polymorphisms integrin alpha2beta1 C807T and GPVI Q317L and risk of ischemic stroke.  Academic Article
• Combined effects of MC4R and FTO common genetic variants on obesity in European general populations.  Academic Article
• Comment on "A common genetic variant is associated with adult and childhood obesity".  Academic Article
• Comment on "DNA from pre-Clovis human coprolites in Oregon, North America".  Academic Article
• Comment on: Valette et al. Melanocortin-4 receptor mutations and polymorphisms do not affect weight loss after bariatric surgery. PLOS ONE 2012; 7(11):E48221.  Academic Article
• Common genetic variation near MC4R is associated with eating behaviour patterns in European populations.  Academic Article
• Common nonsynonymous variants in PCSK1 confer risk of obesity.  Academic Article
• Common variants at 12q14 and 12q24 are associated with hippocampal volume.  Academic Article
• Common variants at MS4A4/MS4A6E, CD2AP, CD33 and EPHA1 are associated with late-onset Alzheimer's disease.  Academic Article
• Common variants at the MHC locus and at chromosome 16q24.1 predispose to Barrett's esophagus.  Academic Article
• Common variants in CACNA1C and MDD susceptibility: A comprehensive meta-analysis.  Academic Article
• Common variants in FTO, MC4R, TMEM18, PRL, AIF1, and PCSK1 show evidence of association with adult obesity in the Greek population.  Academic Article
• Common variants near BDNF and SH2B1 show nominal evidence of association with snacking behavior in European populations.  Academic Article
• Common variants near MC4R are associated with fat mass, weight and risk of obesity.  Academic Article
• Common variation in SIM1 is reproducibly associated with BMI in Pima Indians.  Academic Article
• Comprehensive analysis of genomic variation in the LPA locus and its relationship to plasma lipoprotein(a) in South Asians, Chinese, and European Caucasians.  Academic Article
• Concept, design and implementation of a cardiovascular gene-centric 50 k SNP array for large-scale genomic association studies.  Academic Article
• Concordance of two multiple analytical approaches demonstrate that interaction between BMI and ADIPOQ haplotypes is a determinant of LDL cholesterol in a general French population.  Academic Article
• Contribution of 24 obesity-associated genetic variants to insulin resistance, pancreatic beta-cell function and type 2 diabetes risk in the French population.  Academic Article
• Contribution of BDNF and DRD2 genetic polymorphisms to continued opioid use in patients receiving methadone treatment for opioid use disorder: an observational study.  Academic Article
• Contribution of common non-synonymous variants in PCSK1 to body mass index variation and risk of obesity: a systematic review and meta-analysis with evidence from up to 331 175 individuals.  Academic Article
• Contribution of large region joint associations to complex traits genetics.  Academic Article
• Correction of population stratification in large multi-ethnic association studies.  Academic Article
• Cystic fibrosis modifier genes related to Pseudomonas aeruginosa infection.  Academic Article
• Decreased comfort food intake and allostatic load in adolescents carrying the A3669G variant of the glucocorticoid receptor gene.  Academic Article
• Dense genotyping of immune-related disease regions identifies nine new risk loci for primary sclerosing cholangitis.  Academic Article
• Design of a randomized controlled trial of disclosing genomic risk of coronary heart disease: the Myocardial Infarction Genes (MI-GENES) study.  Academic Article
• Disruption of the ASTN2/TRIM32 locus at 9q33.1 is a risk factor in males for autism spectrum disorders, ADHD and other neurodevelopmental phenotypes.  Academic Article
• Does genetic heterogeneity account for the divergent risk of type 2 diabetes in South Asian and white European populations?  Academic Article
• Dopamine receptors D1 and D2 are related to observed maternal behavior.  Academic Article
• Dose and polymorphic genes xrcc1, xrcc3, gst play a role in the risk of articledeveloping erythema in breast cancer patients following single shot partial breast irradiation after conservative surgery.  Academic Article
• ENPP1 K121Q polymorphism and obesity, hyperglycaemia and type 2 diabetes in the prospective DESIR Study.  Academic Article
• Early detrimental metabolic outcomes of rs17300539-A allele of ADIPOQ gene despite higher adiponectinemia.  Academic Article
• Effect of Bile Acid Sequestrants on the Risk of Cardiovascular Events: A Mendelian Randomization Analysis.  Academic Article
• Effect of ENPP1/PC-1-K121Q and PPARgamma-Pro12Ala polymorphisms on the genetic susceptibility to T2D in the Tunisian population.  Academic Article
• Effect of PON1 Q192R genetic polymorphism on clopidogrel efficacy and cardiovascular events in the Clopidogrel in the Unstable Angina to Prevent Recurrent Events trial and the Atrial Fibrillation Clopidogrel Trial with Irbesartan for Prevention of Vascular Events.  Academic Article
• Effect of genetic variants associated with plasma homocysteine levels on stroke risk.  Academic Article
• Effects of TCF7L2 polymorphisms on obesity in European populations.  Academic Article
• Effects of multiple genetic loci on age at onset in late-onset Alzheimer disease: a genome-wide association study.  Academic Article
• Endocannabinoid receptor 1 gene variations increase risk for obesity and modulate body mass index in European populations.  Academic Article
• Evaluating the association of FAAH common gene variation with childhood, adult severe obesity and type 2 diabetes in the French population.  Academic Article
• Evaluating the transferability of 15 European-derived fasting plasma glucose SNPs in Mexican children and adolescents.  Academic Article
• Evidence of Naturalized Stress-Tolerant Strains of Escherichia coli in Municipal Wastewater Treatment Plants.  Academic Article
• Evidence that Egfr contributes to cryptic genetic variation for photoreceptor determination in natural populations of Drosophila melanogaster.  Academic Article
• Exome sequencing as a diagnostic tool for pediatric-onset ataxia.  Academic Article
• Fine mapping of the insulin-induced gene 2 identifies a variant associated with LDL cholesterol and total apolipoprotein B levels.  Academic Article
• Forty-three loci associated with plasma lipoprotein size, concentration, and cholesterol content in genome-wide analysis.  Academic Article
• Gene × physical activity interactions in obesity: combined analysis of 111,421 individuals of European ancestry.  Academic Article
• Gene- or region-based analysis of genome-wide association studies.  Academic Article
• Gene-centric meta-analysis of lipid traits in African, East Asian and Hispanic populations.  Academic Article
• Genetic Loci associated with C-reactive protein levels and risk of coronary heart disease.  Academic Article
• Genetic Predictors of Cardiovascular Mortality During Intensive Glycemic Control in Type 2 Diabetes: Findings From the ACCORD Clinical Trial.  Academic Article
• Genetic Risk Evaluation in Wet Age-Related Macular Degeneration Treatment Response.  Academic Article
• Genetic analysis of 103 candidate genes for coronary artery disease and associated phenotypes in a founder population reveals a new association between endothelin-1 and high-density lipoprotein cholesterol.  Academic Article
• Genetic analysis of impulsive personality traits: Examination of a priori candidates and genome-wide variation.  Academic Article
• Genetic and functional assessment of the role of the rs13431652-A and rs573225-A alleles in the G6PC2 promoter that are strongly associated with elevated fasting glucose levels.  Academic Article
• Genetic association of rs1344706 in ZNF804A with bipolar disorder and schizophrenia susceptibility in Chinese populations.  Academic Article
• Genetic biomarkers associated with changes in quality of life and pain following palliative radiotherapy in patients with bone metastases.  Academic Article
• Genetic biomarkers associated with pain flare and dexamethasone response following palliative radiotherapy in patients with painful bone metastases.  Academic Article
• Genetic determinants of dabigatran plasma levels and their relation to bleeding.  Academic Article
• Genetic determinants of right-ventricular remodeling after tetralogy of Fallot repair.  Academic Article
• Genetic determinants of warfarin maintenance dose and time in therapeutic treatment range: a RE-LY genomics substudy.  Academic Article
• Genetic dissection of diabetes: facing the giant.  Academic Article
• Genetic influences on ADHD symptom dimensions: Examination of a priori candidates, gene-based tests, genome-wide variation, and SNP heritability.  Academic Article
• Genetic information and the prediction of incident type 2 diabetes in a high-risk multiethnic population: the EpiDREAM genetic study.  Academic Article
• Genetic loci associated with plasma concentration of low-density lipoprotein cholesterol, high-density lipoprotein cholesterol, triglycerides, apolipoprotein A1, and Apolipoprotein B among 6382 white women in genome-wide analysis with replication.  Academic Article
• Genetic relationship between five psychiatric disorders estimated from genome-wide SNPs.  Academic Article
• Genetic risk factors for post-infectious irritable bowel syndrome following a waterborne outbreak of gastroenteritis.  Academic Article
• Genetic variant near IRS1 is associated with type 2 diabetes, insulin resistance and hyperinsulinemia.  Academic Article
• Genetic variants and susceptibility to neurological complications following West Nile virus infection.  Academic Article
• Genetic variants associated with angiotensin-converting enzyme inhibitor-associated angioedema.  Academic Article
• Genetic variants associated with myocardial infarction risk factors in over 8000 individuals from five ethnic groups: The INTERHEART Genetics Study.  Academic Article
• Genetic variants at 2q24 are associated with susceptibility to type 2 diabetes.  Academic Article
• Genetic variants in vitamin d pathway genes and risk of pancreas cancer; results from a population-based case-control study in ontario, Canada.  Academic Article
• Genetic variants of MARCO are associated with susceptibility to pulmonary tuberculosis in a Gambian population.  Academic Article
• Genetic variants of Wnt transcription factor TCF-4 (TCF7L2) putative promoter region are associated with small intestinal Crohn's disease.  Academic Article
• Genetic variation in GIPR influences the glucose and insulin responses to an oral glucose challenge.  Academic Article
• Genetic variation in hyaluronan metabolism loci is associated with plasma plasminogen activator inhibitor-1 concentration.  Academic Article
• Genetic variation in oxytocin rs2740210 and early adversity associated with postpartum depression and breastfeeding duration.  Academic Article
• Genetically determined P2X7 receptor pore formation regulates variability in chronic pain sensitivity.  Academic Article
• Genome wide association identifies common variants at the SERPINA6/SERPINA1 locus influencing plasma cortisol and corticosteroid binding globulin.  Academic Article
• Genome-wide association analysis identifies novel blood pressure loci and offers biological insights into cardiovascular risk.  Academic Article
• Genome-wide association analysis of soluble ICAM-1 concentration reveals novel associations at the NFKBIK, PNPLA3, RELA, and SH2B3 loci.  Academic Article
• Genome-wide association scans identified CTNNBL1 as a novel gene for obesity.  Academic Article
• Genome-wide association studies identify loci associated with age at menarche and age at natural menopause.  Academic Article
• Genome-wide association studies in oesophageal adenocarcinoma and Barrett's oesophagus: a large-scale meta-analysis.  Academic Article
• Genome-wide association studies--data generation, storage, interpretation, and bioinformatics.  Academic Article
• Genome-wide association study for early-onset and morbid adult obesity identifies three new risk loci in European populations.  Academic Article
• Genome-wide meta-analysis identifies 11 new loci for anthropometric traits and provides insights into genetic architecture.  Academic Article
• Genome-wide studies to identify risk factors for kidney disease with a focus on patients with diabetes.  Academic Article
• Germline variation in inflammation-related pathways and risk of Barrett's oesophagus and oesophageal adenocarcinoma.  Academic Article
• Getting closer to p-selectin.  Academic Article
• Give GWAS a Chance.  Academic Article
• Glucocorticoid Receptors, Brain-Derived Neurotrophic Factor, Serotonin and Dopamine Neurotransmission are Associated with Interferon-Induced Depression.  Academic Article
• Growth Differentiation Factor 15 as a Novel Biomarker for Metformin.  Academic Article
• HS3ST1 genotype regulates antithrombin's inflammomodulatory tone and associates with atherosclerosis.  Academic Article
• Hierarchical investigation of genetic influences on response inhibition in healthy young adults.  Academic Article
• High resolution mapping in the major histocompatibility complex region identifies multiple independent novel loci for psoriatic arthritis.  Academic Article
• Hundreds of variants clustered in genomic loci and biological pathways affect human height.  Academic Article
• IFITM3 and susceptibility to respiratory viral infections in the community.  Academic Article
• IL-10RA truncation mutations and Semite populations.  Academic Article
• IL28B polymorphism (rs12979860) associated with clearance of HCV infection in Poland: systematic review of its prevalence in chronic hepatitis C patients and general population frequency.  Academic Article
• Identification and functional analysis of CITED2 mutations in patients with congenital heart defects.  Academic Article
• Identification of Functional and Expression Polymorphisms Associated With Risk for Antineutrophil Cytoplasmic Autoantibody-Associated Vasculitis.  Academic Article
• Identification of SNPs in interferon gamma, interleukin-22, and their receptors and associations with health and production-related traits in Canadian Holstein bulls.  Academic Article
• Identification of a new delta chain hemoglobin variant in a beta-thalassemia carrier: Hb A2-mumc [delta13(a10)Ala-->Asp].  Academic Article
• Identification of genetic variants associated with susceptibility to West Nile virus neuroinvasive disease.  Academic Article
• Identification of new susceptibility loci for type 2 diabetes and shared etiological pathways with coronary heart disease.  Academic Article
• Identification of single nucleotide polymorphisms in the bovine interleukin-12 and interleukin-23 receptor genes and their associations with health and production traits in Holstein cows.  Academic Article
• Immunochip analysis identifies multiple susceptibility loci for systemic sclerosis.  Academic Article
• Impact of a Genetic Risk Score on Myocardial Infarction Risk Across Different Ethnic Populations.  Academic Article
• Impact of common type 2 diabetes risk polymorphisms in the DESIR prospective study.  Academic Article
• Impact of type 2 diabetes susceptibility variants on quantitative glycemic traits reveals mechanistic heterogeneity.  Academic Article
• Implication of the Pro12Ala polymorphism of the PPAR-gamma 2 gene in type 2 diabetes and obesity in the French population.  Academic Article
• Incorporating a Genetic Risk Score Into Coronary Heart Disease Risk Estimates: Effect on Low-Density Lipoprotein Cholesterol Levels (the MI-GENES Clinical Trial).  Academic Article
• Increased substitution rates surrounding low-complexity regions within primate proteins.  Academic Article
• Individual common variants exert weak effects on the risk for autism spectrum disorders.  Academic Article
• Influence of RGS2 on sertraline treatment for social anxiety disorder.  Academic Article
• Inhibition of metabotropic glutamate receptor signaling by the huntingtin-binding protein optineurin.  Academic Article
• Initial evidence that OPRM1 genotype moderates ventral and dorsal striatum functional connectivity during alcohol cues.  Academic Article
• Insights into the development and evolution of exaggerated traits using de novo transcriptomes of two species of horned scarab beetles.  Academic Article
• Interaction between oxytocin genotypes and early experience predicts quality of mothering and postpartum mood.  Academic Article
• Investigation of genetic variants, birthweight and hypothalamic-pituitary-adrenal axis function suggests a genetic variant in the SERPINA6 gene is associated with corticosteroid binding globulin in the western Australia pregnancy cohort (Raine) study.  Academic Article
• Is There a Genetic Predisposition to Anterior Cruciate Ligament Tear? A Systematic Review.  Academic Article
• Is glutamate decarboxylase 2 (GAD2) a genetic link between low birth weight and subsequent development of obesity in children?  Academic Article
• K45R variant of squalene synthase increases total cholesterol levels in two study samples from a French Canadian population.  Academic Article
• Kinematic analysis of Drosophila larval locomotion in response to intermittent light pulses.  Academic Article
• Lack of association between IL-6-174G/C gene polymorphism and Chagas disease.  Academic Article
• Lack of association between the Trp719Arg polymorphism in kinesin-like protein-6 and coronary artery disease in 19 case-control studies.  Academic Article
• Lack of association between type 2 diabetes and major depression: epidemiologic and genetic evidence in a multiethnic population.  Academic Article
• Lack of association of CD36 SNPs with early onset obesity: a meta-analysis in 9,973 European subjects.  Academic Article
• Lack of association of ghrelin precursor gene variants and percentage body fat or serum lipid profiles.  Academic Article
• Large meta-analysis of genome-wide association studies identifies five loci for lean body mass.  Academic Article
• Large-scale association analysis identifies 13 new susceptibility loci for coronary artery disease.  Academic Article
• Large-scale gene-centric meta-analysis across 32 studies identifies multiple lipid loci.  Academic Article
• Leveraging cell type specific regulatory regions to detect SNPs associated with tissue factor pathway inhibitor plasma levels.  Academic Article
• Linkage analysis for three coagulation factors clustering on chromosome 13q34: factor VII, factor X and protein Z.  Academic Article
• Linkage and association analysis in pedigrees from different populations.  Academic Article
• Local-scale patterns of genetic variability, outcrossing, and spatial structure in natural stands of Arabidopsis thaliana.  Academic Article
• Loci related to metabolic-syndrome pathways including LEPR,HNF1A, IL6R, and GCKR associate with plasma C-reactive protein: the Women's Genome Health Study.  Academic Article
• Longitudinal data analysis in genome-wide association studies.  Academic Article
• Longitudinal relationships between glycemic status and body mass index in a multiethnic study: evidence from observational and genetic epidemiology.  Academic Article
• Maternal childhood adversity and child temperament: an association moderated by child 5-HTTLPR genotype.  Academic Article
• Mendelian randomisation, triglycerides, and CHD.  Academic Article
• Mendelian randomization analysis supports the causal role of dysglycaemia and diabetes in the risk of coronary artery disease.  Academic Article
• Meta-analysis identifies 13 new loci associated with waist-hip ratio and reveals sexual dimorphism in the genetic basis of fat distribution.  Academic Article
• Meta-analysis in more than 17,900 cases of ischemic stroke reveals a novel association at 12q24.12.  Academic Article
• Meta-analysis of 74,046 individuals identifies 11 new susceptibility loci for Alzheimer's disease.  Academic Article
• Meta-analysis of Dense Genecentric Association Studies Reveals Common and Uncommon Variants Associated with Height.  Academic Article
• Meta-analysis of SNPs involved in variance heterogeneity using Levene's test for equal variances.  Academic Article
• Meta-analysis of genetic association studies under heterogeneity.  Academic Article
• Methylenetetrahydrofolate reductase gene variant (MTHFR C677T) and migraine: a case control study and meta-analysis.  Academic Article
• Mineralocorticoid receptor genotype moderates the association between physical neglect and serum BDNF.  Academic Article
• Moderators of naltrexone's effects on drinking, urge, and alcohol effects in non-treatment-seeking heavy drinkers in the natural environment.  Academic Article
• Modulation of GLP-1 Levels by a Genetic Variant That Regulates the Cardiovascular Effects of Intensive Glycemic Control in ACCORD.  Academic Article
• Molecular breakpoint mapping of 6q11-q14 interstitial deletions in seven patients.  Academic Article
• Molecular genetic analysis of severe protein C deficiency.  Academic Article
• Multi-ethnic genetic association study of carotid intima-media thickness using a targeted cardiovascular SNP microarray.  Academic Article
• Multigene panels in prostate cancer risk assessment.  Academic Article
• Multigene panels in prostate cancer risk assessment: a systematic review.  Academic Article
• Multilocus sequence analyses reveal extensive diversity and multiple origins of fluconazole resistance in Candida tropicalis from tropical China.  Academic Article
• Multiple apical plasma membrane constituents are associated with susceptibility to meconium ileus in individuals with cystic fibrosis.  Academic Article
• Multiple loci associated with indices of renal function and chronic kidney disease.  Academic Article
• Multiple recurrent genetic events converge on control of histone lysine methylation in medulloblastoma.  Academic Article
• Multivariate analysis of complex gene expression and clinical phenotypes with genetic marker data.  Academic Article
• Mycoplasma genitalium Antibiotic Resistance-Mediating Mutations in Canadian Women With or Without Chlamydia Trachomatis Infection.  Academic Article
• NADPH oxidase complex and IBD candidate gene studies: identification of a rare variant in NCF2 that results in reduced binding to RAC2.  Academic Article
• NCAM1-TTC12-ANKK1-DRD2 variants and smoking motives as intermediate phenotypes for nicotine dependence.  Academic Article
• NOD2/CARD15 gene variants are linked to failure of antibiotic treatment in perianal fistulating Crohn's disease.  Academic Article
• New Locus for Skin Intrinsic Fluorescence in Type 1 Diabetes Also Associated With Blood and Skin Glycated Proteins.  Academic Article
• New genetic loci implicated in fasting glucose homeostasis and their impact on type 2 diabetes risk.  Academic Article
• New tools for investigating the comparative biology of Caenorhabditis briggsae and C. elegans.  Academic Article
• No contribution of angiotensin-converting enzyme (ACE) gene variants to severe obesity: a model for comprehensive case/control and quantitative cladistic analysis of ACE in human diseases.  Academic Article
• Non-synonymous polymorphisms in melanocortin-4 receptor protect against obesity: the two facets of a Janus obesity gene.  Academic Article
• Novel approach identifies SNPs in SLC2A10 and KCNK9 with evidence for parent-of-origin effect on body mass index.  Academic Article
• Novel association of ABO histo-blood group antigen with soluble ICAM-1: results of a genome-wide association study of 6,578 women.  Academic Article
• Novel association of HK1 with glycated hemoglobin in a non-diabetic population: a genome-wide evaluation of 14,618 participants in the Women's Genome Health Study.  Academic Article
• Novel associations of CPS1, MUT, NOX4, and DPEP1 with plasma homocysteine in a healthy population: a genome-wide evaluation of 13 974 participants in the Women's Genome Health Study.  Academic Article
• Novel loci for adiponectin levels and their influence on type 2 diabetes and metabolic traits: a multi-ethnic meta-analysis of 45,891 individuals.  Academic Article
• Novel loci, including those related to Crohn disease, psoriasis, and inflammation, identified in a genome-wide association study of fibrinogen in 17 686 women: the Women's Genome Health Study.  Academic Article
• Novel variants of the IL-10 receptor 1 affect inhibition of monocyte TNF-alpha production.  Academic Article
• Obesity genes and risk of major depressive disorder in a multiethnic population: a cross-sectional study.  Academic Article
• On the use of variance per genotype as a tool to identify quantitative trait interaction effects: a report from the Women's Genome Health Study.  Academic Article
• Parental and child genetic contributions to obesity traits in early life based on 83 loci validated in adults: the FAMILY study.  Academic Article
• Parental and offspring contribution of genetic markers of adult blood pressure in early life: The FAMILY study.  Academic Article
• Passive cigarette smoke exposure during various periods of life, genetic variants, and breast cancer risk among never smokers.  Academic Article
• Penetrance of Polygenic Obesity Susceptibility Loci across the Body Mass Index Distribution.  Academic Article
• Phase II trial of vorinostat in advanced melanoma.  Academic Article
• Phenotypic variability associated with progranulin haploinsufficiency in patients with the common 1477C-->T (Arg493X) mutation: an international initiative.  Academic Article
• Phylogenetic analysis of emergent Streptococcus pneumoniae serotype 22F causing invasive pneumococcal disease using whole genome sequencing.  Academic Article
• Phylogenetic relationship and virulence inference of Streptococcus Anginosus Group: curated annotation and whole-genome comparative analysis support distinct species designation.  Academic Article
• Physical activity and genetic predisposition to obesity in a multiethnic longitudinal study.  Academic Article
• PlexinA polymorphisms mediate the developmental trajectory of human corpus callosum microstructure.  Academic Article
• Polymorphic variation of genes in the fibrinolytic system and the risk of ovarian cancer.  Academic Article
• Polymorphism in the CETP gene region, HDL cholesterol, and risk of future myocardial infarction: Genomewide analysis among 18 245 initially healthy women from the Women's Genome Health Study.  Academic Article
• Polymorphisms in the amino acid transporter solute carrier family 6 (neurotransmitter transporter) member 14 gene contribute to polygenic obesity in French Caucasians.  Academic Article
• Polymorphisms in the gene encoding bovine interleukin-10 receptor alpha are associated with Mycobacterium avium ssp. paratuberculosis infection status.  Academic Article
• Polymorphisms near TBX5 and GDF7 are associated with increased risk for Barrett's esophagus.  Academic Article
• Polymorphisms of 5-HTT LPR and GNβ3 825C>T and Response to Antidepressant Treatment in Functional Dyspepsia: A Study from The Functional Dyspepsia Treatment Trial.  Academic Article
• Population-based genomewide genetic analysis of common clinical chemistry analytes.  Academic Article
• Post genome-wide association studies of novel genes associated with type 2 diabetes show gene-gene interaction and high predictive value.  Academic Article
• Prader-Willi syndrome and Tay-Sachs disease in association with mixed maternal uniparental isodisomy and heterodisomy 15 in a girl who also had isochromosome Xq.  Academic Article
• Preeclampsia does not share common risk alleles in 9p21 with coronary artery disease and type 2 diabetes.  Academic Article
• Prevalence of loss-of-function FTO mutations in lean and obese individuals.  Academic Article
• R125W coding variant in TBC1D1 confers risk for familial obesity and contributes to linkage on chromosome 4p14 in the French population.  Academic Article
• RNA-Seq effectively monitors gene expression in Eutrema salsugineum plants growing in an extreme natural habitat and in controlled growth cabinet conditions.  Academic Article
• Rank-based genome-wide analysis reveals the association of ryanodine receptor-2 gene variants with childhood asthma among human populations.  Academic Article
• Ranking and characterization of established BMI and lipid associated loci as candidates for gene-environment interactions.  Academic Article
• Rapid screening of microsatellite markers for polymorphisms using SYBR green I and a DNA sequencer.  Academic Article
• Rare DNA copy number variants in cardiovascular malformations with extracardiac abnormalities.  Academic Article
• Rare coding variants in PLCG2, ABI3, and TREM2 implicate microglial-mediated innate immunity in Alzheimer's disease.  Academic Article
• Rationale and design of GENEiUS: a prospective observational study on the genetic and environmental determinants of body mass index evolution in Canadian undergraduate students.  Academic Article
• Reduced hippocampus volume and memory performance in bipolar disorder patients carrying the BDNF val66met met allele.  Academic Article
• Relations between lipoprotein(a) concentrations, LPA genetic variants, and the risk of mortality in patients with established coronary heart disease: a molecular and genetic association study.  Academic Article
• Renin-angiotensin and endothelial nitric oxide synthase gene polymorphisms are not associated with the risk of incident type 2 diabetes mellitus: a prospective cohort study.  Academic Article
• Replication of genetic associations with plasma lipoprotein traits in a multiethnic sample.  Academic Article
• Resequencing genomic DNA of patients with severe hypertriglyceridemia (MIM 144650).  Academic Article
• Results of a pilot multicenter genotype-based randomized placebo-controlled trial of propranolol to reduce pain after major thermal burn injury.  Academic Article
• Risk Alleles in/near ADCY5, ADRA2A, CDKAL1, CDKN2A/B, GRB10, and TCF7L2 Elevate Plasma Glucose Levels at Birth and in Early Childhood: Results from the FAMILY Study.  Academic Article
• Role of the IFNG +874T/A polymorphism in Chagas disease in a Colombian population.  Academic Article
• SNPs and coronary heart disease.  Academic Article
• SNPs in DNA repair or oxidative stress genes and late subcutaneous fibrosis in patients following single shot partial breast irradiation.  Academic Article
• SNPs in the bovine IL-10 receptor are associated with somatic cell score in Canadian dairy bulls.  Academic Article
• SNPs in the neural cell adhesion molecule 1 gene (NCAM1) may be associated with human neural tube defects.  Academic Article
• Second-pandemic strain of Vibrio cholerae from the Philadelphia cholera outbreak of 1849.  Academic Article
• Secretory granule neuroendocrine protein 1 (SGNE1) genetic variation and glucose intolerance in severe childhood and adult obesity.  Academic Article
• Secukinumab, a human anti-IL-17A monoclonal antibody, for moderate to severe Crohn's disease: unexpected results of a randomised, double-blind placebo-controlled trial.  Academic Article
• Selected polymorphisms in sex hormone-related genes, circulating sex hormones and risk of endometrial cancer.  Academic Article
• Sex- and age-interacting eQTLs in human complex diseases.  Academic Article
• Should we have blind faith in bioinformatics software? Illustrations from the SNAP web-based tool.  Academic Article
• Single nucleotide polymorphism in IL1B is associated with infection risk in paediatric acute myeloid leukaemia.  Academic Article
• Single nucleotide polymorphisms alter the promoter activity of bovine MIF.  Academic Article
• Single nucleotide polymorphisms in the ectomycorrhizal mushroom Tricholoma matsutake.  Academic Article
• Single nucleotide polymorphisms in the neuropeptide Y2 receptor (NPY2R) gene and association with severe obesity in French white subjects.  Academic Article
• Smith-Lemli-Opitz syndrome: carrier frequency and spectrum of DHCR7 mutations in Canada.  Academic Article
• Stationary phase-induction of G-->T mutations in Escherichia coli.  Academic Article
• Statistical genetics with application to population-based study design: a primer for clinicians.  Academic Article
• Structural variation of chromosomes in autism spectrum disorder.  Academic Article
• Study of TNFalpha -308G/A and IL6 -174G/C polymorphisms in type 2 diabetes and obesity risk in the Tunisian population.  Academic Article
• TCF7L2 is associated with type 2 diabetes in nonobese individuals from Tunisia.  Academic Article
• TCF7L2 rs7903146 variant does not associate with smallness for gestational age in the French population.  Academic Article
• TLR5 as an anti-inflammatory target and modifier gene in cystic fibrosis.  Academic Article
• TNF-alpha-308 G/A polymorphism and responsiveness to TNF-alpha blockade therapy in moderate to severe rheumatoid arthritis: a systematic review and meta-analysis.  Academic Article
• The 9p21.3 locus and cardiovascular risk in familial hypercholesterolemia.  Academic Article
• The LASSO and sparse least square regression methods for SNP selection in predicting quantitative traits.  Academic Article
• The Q121 variant of ENPP1 may protect from childhood overweight/obesity in the Italian population.  Academic Article
• The T-381C SNP in BNP gene may be modestly associated with type 2 diabetes: an updated meta-analysis in 49 279 subjects.  Academic Article
• The effect of chromosome 9p21 variants on cardiovascular disease may be modified by dietary intake: evidence from a case/control and a prospective study.  Academic Article
• The functional variant rs1048990 in PSMA6 is associated with susceptibility to myocardial infarction in a Chinese population.  Academic Article
• The genetic susceptibility to type 2 diabetes may be modulated by obesity status: implications for association studies.  Academic Article
• The genetics of human personality.  Academic Article
• The human ortholog of acid-sensing ion channel gene ASIC1a is associated with panic disorder and amygdala structure and function.  Academic Article
• The imprinted gene neuronatin is regulated by metabolic status and associated with obesity.  Academic Article
• The need for inclusion of sex and age of onset variables in genetic association studies of obsessive-compulsive disorder: Overview.  Academic Article
• The protective effect of the obesity-associated rs9939609 A variant in fat mass- and obesity-associated gene on depression.  Academic Article
• The value of studying gene-environment interactions in culturally diverse populations.  Academic Article
• Thinking and doing: the effects of dopamine and oxytocin genes and executive function on mothering behaviours.  Academic Article
• Thirty new loci for age at menarche identified by a meta-analysis of genome-wide association studies.  Academic Article
• Three new beta-globin gene promoter mutations identified through newborn screening.  Academic Article
• Thrombophilia and location of venous thromboembolism.  Academic Article
• Thymic stromal lymphopoietin (TSLP) secretion from human nasal epithelium is a function of TSLP genotype.  Academic Article
• Two new Loci for body-weight regulation identified in a joint analysis of genome-wide association studies for early-onset extreme obesity in French and german study groups.  Academic Article
• Type 2 diabetes whole-genome association study in four populations: the DiaGen consortium.  Academic Article
• Update on bipolar disorder biomarker candidates.  Academic Article
• Use of breed-specific single nucleotide polymorphisms to discriminate between Holstein and Jersey dairy cattle breeds.  Academic Article
• Variants in the fetal genome near FLT1 are associated with risk of preeclampsia.  Academic Article
• Variation at the DPP4 locus influences apolipoprotein B levels in South Asians and exhibits heterogeneity in Europeans related to BMI.  Academic Article
• Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study.  Academic Article
• Variation in FTO contributes to childhood obesity and severe adult obesity.  Academic Article
• Vascular endothelial growth factor polymorphisms and esophageal cancer prognosis.  Academic Article
• Vitamin D-related genetic variants, interactions with vitamin D exposure, and breast cancer risk among Caucasian women in Ontario.  Academic Article
• Whole genome sequencing resource identifies 18 new candidate genes for autism spectrum disorder.  Academic Article
• Whole-genome SNP association in the horse: identification of a deletion in myosin Va responsible for Lavender Foal Syndrome.  Academic Article
• Within-group relatedness is correlated with colony-level social structure and reproductive sharing in a social fish.  Academic Article
• Yersinia pestis: new evidence for an old infection.  Academic Article
• [Study on polymorphisms of genes with susceptibility to drug induced liver injury in a cohort receiving anti-tuberculosis treatment].  Academic Article
• β+-Thalassemia trait due to a novel mutation in the β-globin gene promoter: -26 (A>C) [HBB c.-76A>C].  Academic Article