Journal article
Effect of Genetic Variants Associated With Plasma Homocysteine Levels on Stroke Risk
Abstract
BACKGROUND AND PURPOSE: Elevated total plasma homocysteine (tHcy) levels are known to be associated with increased risk of ischemic stroke (IS). Given that both tHcy and IS are heritable traits, we investigated a potential genetic relationship between homocysteine levels and stroke risk by assessing 18 polymorphisms previously associated with tHcy levels for their association with IS and its subtypes.
METHODS: Previous meta-analysis results …
Authors
Cotlarciuc I; Malik R; Holliday EG; Ahmadi KR; Paré G; Psaty BM; Fornage M; Hasan N; Rinne PE; Ikram MA
Journal
Stroke, Vol. 45, No. 7, pp. 1920–1924
Publisher
Wolters Kluwer
Publication Date
July 2014
DOI
10.1161/strokeaha.114.005208
ISSN
0039-2499