Journal article
Cannabis use and risk of schizophrenia: a Mendelian randomization study
Abstract
Cannabis use is observationally associated with an increased risk of schizophrenia, but whether the relationship is causal is not known. Using a genetic approach, we took 10 independent genetic variants previously identified to associate with cannabis use in 32 330 individuals to determine the nature of the association between cannabis use and risk of schizophrenia. Genetic variants were employed as instruments to recapitulate a randomized …
Authors
Vaucher J; Keating BJ; Lasserre AM; Gan W; Lyall DM; Ward J; Smith DJ; Pell JP; Sattar N; Paré G
Journal
Molecular Psychiatry, Vol. 23, No. 5, pp. 1287–1292
Publisher
Springer Nature
Publication Date
May 2018
DOI
10.1038/mp.2016.252
ISSN
1359-4184