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Genome-wide association studies in oesophageal...
Journal article

Genome-wide association studies in oesophageal adenocarcinoma and Barrett's oesophagus: a large-scale meta-analysis

Abstract

BACKGROUND: Oesophageal adenocarcinoma represents one of the fastest rising cancers in high-income countries. Barrett's oesophagus is the premalignant precursor of oesophageal adenocarcinoma. However, only a few patients with Barrett's oesophagus develop adenocarcinoma, which complicates clinical management in the absence of valid predictors. Within an international consortium investigating the genetics of Barrett's oesophagus and oesophageal …

Authors

Gharahkhani P; Fitzgerald RC; Vaughan TL; Palles C; Gockel I; Tomlinson I; Buas MF; May A; Gerges C; Anders M

Journal

The Lancet Oncology, Vol. 17, No. 10, pp. 1363–1373

Publisher

Elsevier

Publication Date

October 2016

DOI

10.1016/s1470-2045(16)30240-6

ISSN

1470-2045