Journal article
Genome-wide association study identifies a novel maternal gene × stress interaction associated with spontaneous preterm birth
Abstract
BackgroundMaternal stress is potentially a modifiable risk factor for spontaneous preterm birth (sPTB). However, epidemiologic findings on the maternal stress−sPTB relationship have been inconsistent.MethodsTo investigate whether the maternal stress−sPTB associations may be modified by genetic susceptibility, we performed genome-wide gene × stress interaction analyses in 1490 African-American women from the Boston Birth cohort who delivered …
Authors
Hong X; Surkan PJ; Zhang B; Keiser A; Ji Y; Ji H; Burd I; Bustamante-Helfrich B; Ogunwole SM; Tang W-Y
Journal
Pediatric Research, Vol. 89, No. 6, pp. 1549–1556
Publisher
Springer Nature
Publication Date
May 2021
DOI
10.1038/s41390-020-1093-1
ISSN
0031-3998