Journal article
StrandAdvantage test for early‐line and advanced‐stage treatment decisions in solid tumors
Abstract
Comprehensive genetic profiling of tumors using next-generation sequencing (NGS) is gaining acceptance for guiding treatment decisions in cancer care. We designed a cancer profiling test combining both deep sequencing and immunohistochemistry (IHC) of relevant cancer targets to aid therapy choices in both standard-of-care (SOC) and advanced-stage treatments for solid tumors. The SOC report is provided in a short turnaround time for four tumors, …
Authors
Sen M; Katragadda S; Ravichandran A; Deshpande G; Parulekar M; Nayanala S; Vittal V; Shen W; Yong MPN; Jacob J
Journal
Cancer Medicine, Vol. 6, No. 5, pp. 883–901
Publisher
Wiley
Publication Date
May 2017
DOI
10.1002/cam4.1037
ISSN
2045-7634
Associated Experts
Fields of Research (FoR)
Medical Subject Headings (MeSH)
Cell Line, TumorDNA Copy Number VariationsDNA, NeoplasmGenetic Association StudiesGenetic Predisposition to DiseaseHigh-Throughput Nucleotide SequencingHumansImmunohistochemistryNeoplasmsPolymorphism, Single NucleotideReproducibility of ResultsSequence Analysis, DNAStandard of CareTranslocation, Genetic