Journal article
Genetic determinants of plasma triglycerides
Abstract
Plasma triglyceride (TG) concentration is reemerging as an important cardiovascular disease risk factor. More complete understanding of the genes and variants that modulate plasma TG should enable development of markers for risk prediction, diagnosis, prognosis, and response to therapies and might help specify new directions for therapeutic interventions. Recent genome-wide association studies (GWAS) have identified both known and novel loci …
Authors
Johansen CT; Kathiresan S; Hegele RA
Journal
Journal of Lipid Research, Vol. 52, No. 2, pp. 189–206
Publisher
Elsevier
Publication Date
2 2011
DOI
10.1194/jlr.r009720
ISSN
0022-2275
Associated Experts
Fields of Research (FoR)
Sustainable Development Goals (SDG)
Medical Subject Headings (MeSH)
Adaptor Proteins, Signal TransducingAngiopoietin-Like Protein 3Angiopoietin-like ProteinsAngiopoietinsApolipoprotein A-VApolipoprotein C-IIIApolipoproteins AApolipoproteins BBasic Helix-Loop-Helix Leucine Zipper Transcription FactorsCarrier ProteinsCoronary Artery DiseaseDyslipidemiasFatty Acid DesaturasesFemaleFibric AcidsGenome-Wide Association StudyHumansHypertriglyceridemiaIntracellular Signaling Peptides and ProteinsLipid MetabolismLipid Metabolism DisordersLipoprotein LipaseMaleMembrane ProteinsNiacinPhospholipid Transfer ProteinsPolymorphism, Single NucleotideProtein Serine-Threonine KinasesReceptors, LipoproteinRiskTriglyceridesUpstream Stimulatory FactorsWhite People