Journal article
Elevated Lipoprotein(a) and Risk of Atrial Fibrillation An Observational and Mendelian Randomization Study
Abstract
Background Atrial fibrillation (AF) is a cardiac arrhythmia associated with an elevated risk of stroke, heart failure, and mortality. However, preventative therapies are needed with ancillary benefits on its cardiovascular comorbidities. Lipoprotein(a) (Lp[a]) is a recognized risk factor for atherosclerotic cardiovascular disease (ASCVD), which itself increases AF risk, but it remains unknown whether Lp(a) is a causal mediator of AF independent …
Authors
Mohammadi-Shemirani P; Chong M; Narula S; Perrot N; Conen D; Roberts JD; Thériault S; Bossé Y; Lanktree MB; Pigeyre M
Journal
Journal of the American College of Cardiology, Vol. 79, No. 16, pp. 1579–1590
Publisher
Elsevier
Publication Date
April 2022
DOI
10.1016/j.jacc.2022.02.018
ISSN
0735-1097