Journal article
Genome-wide association analyses for lung function and chronic obstructive pulmonary disease identify new loci and potential druggable targets
Abstract
Louise Wain, Ian Hall, Martin Tobin and colleagues report genome-wide association analyses of lung function, identifying 43 new signals associated with one or more lung function traits. A genetic risk score derived from these results was significantly associated with risk for chronic obstructive pulmonary disease in independent populations.
Authors
Wain LV; Shrine N; Artigas MS; Erzurumluoglu AM; Noyvert B; Bossini-Castillo L; Obeidat M; Henry AP; Portelli MA; Hall RJ
Journal
Nature Genetics, Vol. 49, No. 3, pp. 416–425
Publisher
Springer Nature
Publication Date
March 2017
DOI
10.1038/ng.3787
ISSN
1061-4036