Journal article
Relationship between Genetic Risk and Age of Diagnosis of Systemic Lupus Erythematosus
Abstract
OBJECTIVE: Specific risk alleles for childhood-onset systemic lupus erythematosus SLE (cSLE) vs adult-onset SLE (aSLE) patients have not been identified. The aims of this study were to determine if there is an association (1) between non-HLA-related genetic risk score (GRS) and age of SLE diagnosis, and (2) between HLA-related GRS and age of SLE diagnosis.
METHODS: Genomic DNA was obtained from 2001 multiethnic patients and genotyped using the …
Authors
Dominguez D; Kamphuis S; Beyene J; Wither J; Harley JB; Blanco I; Vila-Inda C; Brunner H; Klein-Gitleman M; McCurdy D
Journal
The Journal of Rheumatology, Vol. 48, No. 6, pp. 852–858
Publisher
The Journal of Rheumatology
Publication Date
6 2021
DOI
10.3899/jrheum.200002
ISSN
0315-162X