Journal article
Physical activity and genetic predisposition to obesity in a multiethnic longitudinal study
Abstract
Physical activity (PA) has been shown to reduce the impact of FTO variation and obesity genetic risk scores (GRS) on BMI. We examined this interaction using a quantitative measure of PA and two adiposity indexes in a longitudinal multi-ethnic study. We analyzed the impact of PA on the association between 14 obesity predisposing variants (analyzed independently and as a GRS) and baseline/follow-up obesity measures in the multi-ethnic prospective …
Authors
Reddon H; Gerstein HC; Engert JC; Mohan V; Bosch J; Desai D; Bailey SD; Diaz R; Yusuf S; Anand SS
Journal
Scientific Reports, Vol. 6, No. 1,
Publisher
Springer Nature
DOI
10.1038/srep18672
ISSN
2045-2322