A DNA Switch for Detecting Single Nucleotide Polymorphism within a Long DNA Sequence Under Denaturing Conditions Academic Article uri icon

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abstract

  • Invited for the cover of this issue is the group of Yingfu Li at McMaster University. The image depicts a molecular switch for ultra-specific detection of DNA utilizing a guanine-quadruplex (up-right structure) resistant to denaturation by urea (ball-and-stick structures). Read the full text of the article at 10.1002/chem.201903536.

authors

  • Zhang, Wenqing
  • Li, Jiuxing
  • Salena, Bruno
  • Li, Yingfu

publication date

  • January 13, 2020