Genome-wide association analysis identifies novel...

Genome-wide association analysis identifies novel blood pressure loci and offers biological insights into cardiovascular risk

Abstract

Mark Caulfield, Paul Elliott and colleagues use data from the UK Biobank to perform genome-wide association analysis for blood pressure traits. They identify and validate 107 novel loci and highlight new biological pathways for potential therapeutic intervention for hypertension.

Authors

Warren HR; Evangelou E; Cabrera CP; Gao H; Ren M; Mifsud B; Ntalla I; Surendran P; Liu C; Cook JP

Journal

Nature Genetics, Vol. 49, No. 3, pp. 403–415

Publisher

Springer Nature

Publication Date

March 1, 2017

DOI

10.1038/ng.3768

ISSN

1061-4036

Associated Experts

Guillaume Pare

Professor, Faculty of Health Sciences

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