Journal article
Favourable IFNL3 Genotypes Are Associated with Spontaneous Clearance and Are Differentially Distributed in Aboriginals in Canadian HIV-Hepatitis C Co-Infected Individuals
Abstract
Canadian Aboriginals are reported to clear Hepatitis C (HCV) more frequently. We tested the association of spontaneous clearance and three single nucleotide polymorphisms (SNPs) near the Interferon-lambda 3 (IFNL3) gene (rs12979860, rs8099917, functional variant rs8103142) and compared the SNP frequencies between HIV-HCV co-infected whites and Aboriginals from the Canadian Co-infection Cohort. HCV treatment-naïve individuals with at least two …
Authors
Moqueet N; Infante-Rivard C; Platt R; Young J; Cooper C; Hull M; Walmsley S; Klein M; Investigators T
Journal
International Journal of Molecular Sciences, Vol. 16, No. 3, pp. 6496–6512
Publisher
MDPI
DOI
10.3390/ijms16036496
ISSN
1661-6596