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Multigene panels in prostate cancer risk...
Journal article

Multigene panels in prostate cancer risk assessment: a systematic review

Abstract

PURPOSE: Single-nucleotide polymorphism (SNP) panel tests have been proposed for use in the detection of, and prediction of risk for, prostate cancer and as prognostic indicator in affected men. A systematic review was undertaken to address three research questions to evaluate the analytic validity, clinical validity, clinical utility, and prognostic validity of SNP-based panels. METHODS: Data sources comprised MEDLINE, Cochrane CENTRAL, …

Authors

Little J; Wilson B; Carter R; Walker K; Santaguida P; Tomiak E; Beyene J; Usman Ali M; Raina P

Journal

Genetics in Medicine, Vol. 18, No. 6, pp. 535–544

Publisher

Elsevier

Publication Date

June 2016

DOI

10.1038/gim.2015.125

ISSN

1098-3600