Journal article
COL4A2 is associated with lacunar ischemic stroke and deep ICH
Abstract
OBJECTIVE: To determine whether common variants in familial cerebral small vessel disease (SVD) genes confer risk of sporadic cerebral SVD.
METHODS: We meta-analyzed genotype data from individuals of European ancestry to determine associations of common single nucleotide polymorphisms (SNPs) in 6 familial cerebral SVD genes (COL4A1, COL4A2, NOTCH3, HTRA1, TREX1, and CECR1) with intracerebral hemorrhage (ICH) (deep, lobar, all; 1,878 cases, …
Authors
Rannikmäe K; Sivakumaran V; Millar H; Malik R; Anderson CD; Chong M; Dave T; Falcone GJ; Fernandez-Cadenas I; Jimenez-Conde J
Journal
Neurology, Vol. 89, No. 17, pp. 1829–1839
Publisher
Wolters Kluwer
Publication Date
October 24, 2017
DOI
10.1212/wnl.0000000000004560
ISSN
0028-3878