Journal article
Polymorphisms Near TBX5 and GDF7 Are Associated With Increased Risk for Barrett’s Esophagus
Abstract
BACKGROUND & AIMS: Barrett's esophagus (BE) increases the risk of esophageal adenocarcinoma (EAC). We found the risk to be BE has been associated with single nucleotide polymorphisms (SNPs) on chromosome 6p21 (within the HLA region) and on 16q23, where the closest protein-coding gene is FOXF1. Subsequently, the Barrett's and Esophageal Adenocarcinoma Consortium (BEACON) identified risk loci for BE and esophageal adenocarcinoma near CRTC1 and …
Authors
Palles C; Chegwidden L; Li X; Findlay JM; Farnham G; Giner FC; Peppelenbosch MP; Kovac M; Adams CL; Prenen H
Journal
Gastroenterology, Vol. 148, No. 2, pp. 367–378
Publisher
Elsevier
Publication Date
2 2015
DOI
10.1053/j.gastro.2014.10.041
ISSN
0016-5085