Journal article
Assessing known chronic kidney disease associated genetic variants in Saudi Arabian populations
Abstract
BackgroundGenome wide association studies of patients with European descent have identified common variants associated with risk of reduced estimated glomerular filtration rate (eGFR). A panel of eight variants were selected to evaluate their association and prevalence in a Saudi Arabian patient cohort with chronic kidney disease (CKD).MethodsEight genetic variants in four genes (SHROOM3, MYH9, SLC7A9, and CST3) were genotyped in 160 CKD …
Authors
Cyrus C; Al-Mueilo S; Vatte C; Chathoth S; Li YR; Qutub H; Al Ali R; Al-Muhanna F; Lanktree MB; Alkharsah KR
Journal
BMC Nephrology, Vol. 19, No. 1,
Publisher
Springer Nature
Publication Date
December 2018
DOI
10.1186/s12882-018-0890-9
ISSN
1471-2369
Fields of Research (FoR)
Medical Subject Headings (MeSH)
AdultAgedAllelesAmino Acid Transport Systems, BasicCase-Control StudiesCholecalciferolCystatin CFemaleFibroblast Growth Factor-23Fibroblast Growth FactorsGenotypeGlomerular Filtration RateHumansMaleMicrofilament ProteinsMiddle AgedMolecular Motor ProteinsMyosin Heavy ChainsPolymorphism, Single NucleotideRenal Insufficiency, ChronicRisk FactorsSaudi Arabia