Journal article
Novel Associations of CPS1, MUT, NOX4, and DPEP1 With Plasma Homocysteine in a Healthy Population
Abstract
BACKGROUND: Homocysteine is a sulfur amino acid whose plasma concentration has been associated with the risk of cardiovascular diseases, neural tube defects, and loss of cognitive function in epidemiological studies. Although genetic variants of MTHFR and CBS are known to influence homocysteine concentration, common genetic determinants of homocysteine remain largely unknown.
METHODS AND RESULTS: To address this issue comprehensively, we …
Authors
Paré G; Chasman DI; Parker AN; Zee RRY; Mälarstig A; Seedorf U; Collins R; Watkins H; Hamsten A; Miletich JP
Journal
Circulation Genomic and Precision Medicine, Vol. 2, No. 2, pp. 142–150
Publisher
Wolters Kluwer
Publication Date
April 2009
DOI
10.1161/circgenetics.108.829804
ISSN
1942-325X