Journal article
Variation at the DPP4 locus influences apolipoprotein B levels in South Asians and exhibits heterogeneity in Europeans related to BMI
Abstract
Aims/hypothesisDyslipidaemia, a common feature of type 2 diabetes, is characterised by an increase in atherogenic particles, quantifiable through apolipoprotein B (ApoB) levels. Genetic studies of lipid levels have focused on Europeans; a study in South Asians could identify novel genes.MethodsWe tested 31,739 single nucleotide polymorphisms (SNPs) from ∼2,000 genes in 2,573 South Asians from the epidemiological arm of the Diabetes Reduction …
Authors
Bailey SD; Xie C; Paré G; Montpetit A; Mohan V; Yusuf S; Gerstein H; Engert JC; Anand SS; on behalf of the EpiDREAM and INTERHEART investigators
Journal
Diabetologia, Vol. 57, No. 4, pp. 738–745
Publisher
Springer Nature
Publication Date
April 2014
DOI
10.1007/s00125-013-3142-3
ISSN
0012-186X