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Novel Association of ABO Histo-Blood Group Antigen...
Journal article

Novel Association of ABO Histo-Blood Group Antigen with Soluble ICAM-1: Results of a Genome-Wide Association Study of 6,578 Women

Abstract

While circulating levels of soluble Intercellular Adhesion Molecule 1 (sICAM-1) have been associated with diverse conditions including myocardial infarction, stroke, malaria, and diabetes, comprehensive analysis of the common genetic determinants of sICAM-1 is not available. In a genome-wide association study conducted among 6,578 participants in the Women's Genome Health Study, we find that three SNPs at the ICAM1 (19p13.2) locus (rs1799969, …

Authors

Paré G; Chasman DI; Kellogg M; Zee RYL; Rifai N; Badola S; Miletich JP; Ridker PM

Journal

PLOS Genetics, Vol. 4, No. 7,

Publisher

Public Library of Science (PLoS)

DOI

10.1371/journal.pgen.1000118

ISSN

1553-7390