Journal article
Genetic Risk Factors for Post-Infectious Irritable Bowel Syndrome Following a Waterborne Outbreak of Gastroenteritis
Abstract
BACKGROUND & AIMS: Acute gastroenteritis is the strongest risk factor for irritable bowel syndrome (IBS). In May 2000, >2300 residents of Walkerton, Ontario, developed gastroenteritis from microbial contamination of the municipal water supply; a longitudinal study found that >36.2% of these developed IBS. We used this cohort to study genetic susceptibility to post-infectious (PI)-IBS.
METHODS: We screened 79 functional variants of genes with …
Authors
Villani A; Lemire M; Thabane M; Belisle A; Geneau G; Garg AX; Clark WF; Moayyedi P; Collins SM; Franchimont D
Journal
Gastroenterology, Vol. 138, No. 4, pp. 1502–1513
Publisher
Elsevier
Publication Date
April 2010
DOI
10.1053/j.gastro.2009.12.049
ISSN
0016-5085