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Discovery of cross-reactive probes and polymorphic...
Journal article

Discovery of cross-reactive probes and polymorphic CpGs in the Illumina Infinium HumanMethylation450 microarray

Abstract

DNA methylation, an important type of epigenetic modification in humans, participates in crucial cellular processes, such as embryonic development, X-inactivation, genomic imprinting and chromosome stability. Several platforms have been developed to study genome-wide DNA methylation. Many investigators in the field have chosen the Illumina Infinium HumanMethylation microarray for its ability to reliably assess DNA methylation following sodium …

Authors

Chen Y-A; Lemire M; Choufani S; Butcher DT; Grafodatskaya D; Zanke BW; Gallinger S; Hudson TJ; Weksberg R

Journal

Epigenetics, Vol. 8, No. 2, pp. 203–209

Publisher

Taylor & Francis

Publication Date

2 2013

DOI

10.4161/epi.23470

ISSN

1559-2294