Journal article
Genotypic and Phenotypic Analyses of Two “Isogenic” Strains of the Human Fungal Pathogen Cryptococcus neoformans var. neoformans
Abstract
The Cryptococcus neoformans species complex is a model organism for fungal studies. Many studies have used two strains, JEC20 and JEC21, and their derivatives. These two strains were obtained through 10 rounds of backcrosses and have been assumed near identical except at the mating-type locus. Here we obtained and compared the JEC20 genome sequence with the published “JEC21” genome. Our comparison revealed 5322 single nucleotide polymorphisms …
Authors
Hua W; Vogan A; Xu J
Journal
Mycopathologia, Vol. 184, No. 2, pp. 195–212
Publisher
Springer Nature
Publication Date
4 2019
DOI
10.1007/s11046-019-00328-9
ISSN
0301-486X