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Dopamine receptors D1 and D2 are related to...
Journal article

Dopamine receptors D1 and D2 are related to observed maternal behavior

Abstract

The dopamine pathway and especially the dopamine receptors 1 and 2 (DRD1 and DRD2) are implicated in the regulation of mothering in rats. Evidence for this in humans is lacking. Here, we show that genetic variation in both DRD1 and DRD2 genes in a sample of 187 Caucasian mothers predicts variation in distinct maternal behaviors during a 30-min mother-infant interaction at 6 months postpartum. Two DRD1 single-nucleotide polymorphisms (SNPs …

Authors

Mileva‐Seitz V; Fleming AS; Meaney MJ; Mastroianni A; Sinnwell JP; Steiner M; Atkinson L; Levitan RD; Matthews SG; Kennedy JL

Journal

Genes Brain & Behavior, Vol. 11, No. 6, pp. 684–694

Publisher

Wiley

Publication Date

August 2012

DOI

10.1111/j.1601-183x.2012.00804.x

ISSN

1601-1848