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A Gene Variant in CERS2 Is Associated with Rate of...
Journal article

A Gene Variant in CERS2 Is Associated with Rate of Increase in Albuminuria in Patients with Diabetes from ONTARGET and TRANSCEND

Abstract

Although albuminuria and subsequent advanced stage chronic kidney disease are common among patients with diabetes, the rate of increase in albuminuria varies among patients. Since genetic variants associated with estimated glomerular filtration rate (eGFR) were identified in cross sectional studies, we asked whether these variants were also associated with rate of increase in albuminuria among patients with diabetes from ONTARGET and …

Authors

Shiffman D; Pare G; Oberbauer R; Louie JZ; Rowland CM; Devlin JJ; Mann JF; McQueen MJ

Journal

PLOS ONE, Vol. 9, No. 9,

Publisher

Public Library of Science (PLoS)

DOI

10.1371/journal.pone.0106631

ISSN

1932-6203