Genome-Wide Association Studies—Data Generation, Storage, Interpretation, and Bioinformatics
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Genome-wide association studies (GWAS) have had great success in identifying common genetic determinants of disease. One of the challenges posed by GWAS is the analysis of the large amount of data generated. This review aims to provide the non-geneticists with an overview of the different steps entailed in analysis of GWAS data, with an emphasis on popular bioinformatics tools available. GWAS data generation, analysis, and interpretation will be covered.
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