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Journal article

Genome-wide studies to identify risk factors for kidney disease with a focus on patients with diabetes

Abstract

Chronic kidney disease (CKD) affects 10-13% of the general population and diabetic nephropathy (DN) is the leading cause of end-stage renal disease (ESRD). In addition to known demographic, biochemical and lifestyle risk factors, genetics is also contributing to CKD risk. In recent years, genome-wide association studies (GWAS) have provided a hypothesis-free approach to identify common genetic variants that could account for the genetic risk …

Authors

Regele F; Jelencsics K; Shiffman D; Paré G; McQueen MJ; Mann JFE; Oberbauer R

Journal

Nephrology Dialysis Transplantation, Vol. 30, No. suppl_4, pp. iv26–iv34

Publisher

Oxford University Press (OUP)

Publication Date

August 2015

DOI

10.1093/ndt/gfv087

ISSN

0931-0509