Journal article
Methylenetetrahydrofolate Reductase Gene Variant (MTHFR C677T) and Migraine: A Case Control Study and Meta-analysis
Abstract
BackgroundMigraine is a common disorder that often coexists with depression. While a functional polymorphism in methyleneterahydrofolate reductase gene (MTHFR C677T) has been implicated in depression; the evidence to support an association of MTHFR with migraine has been inconclusive. We aim to investigate the effect of this variant on propensity for migraine and to perform a systematic review and meta-analysis of studies of MTHFR and migraine …
Authors
Samaan Z; Gaysina D; Cohen-Woods S; Craddock N; Jones L; Korszun A; Owen M; Mente A; McGuffin P; Farmer A
Journal
BMC Neurology, Vol. 11, No. 1,
Publisher
Springer Nature
Publication Date
December 2011
DOI
10.1186/1471-2377-11-66
ISSN
1471-2377