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Causal Relationship between Adiponectin and...
Journal article

Causal Relationship between Adiponectin and Metabolic Traits: A Mendelian Randomization Study in a Multiethnic Population

Abstract

BACKGROUND: Adiponectin, a secretagogue exclusively produced by adipocytes, has been associated with metabolic features, but its role in the development of the metabolic syndrome remains unclear. OBJECTIVES: We investigated the association between serum adiponectin level and metabolic traits, using both observational and genetic epidemiologic approaches in a multiethnic population assembled in Canada.

Authors

Mente A; Meyre D; Lanktree MB; Heydarpour M; Davis AD; Miller R; Gerstein H; Hegele RA; Yusuf S; Anand SS

Journal

PLOS ONE, Vol. 8, No. 6,

Publisher

Public Library of Science (PLoS)

Publication Date

2013

DOI

10.1371/journal.pone.0066808

ISSN

1932-6203