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A genome-wide association study in Europeans and...
Journal article

A genome-wide association study in Europeans and South Asians identifies five new loci for coronary artery disease

Abstract

The Coronary Artery Disease Genetics Consortium report a meta-analysis of genome-wide association studies for coronary artery disease (CAD) in discovery and replication cohorts including both European and South Asian studies. They identify five loci newly associated with CAD.

Authors

Peden JF; Hopewell JC; Saleheen D; Chambers JC; Hager J; Soranzo N; Collins R; Danesh J; Elliott P; Farrall M

Journal

Nature Genetics, Vol. 43, No. 4, pp. 339–344

Publisher

Springer Nature

Publication Date

February 1, 2011

DOI

10.1038/ng.782

ISSN

1061-4036

Associated Experts

Salim Yusuf

Professor, Faculty of Health Sciences
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Sonia Anand

Professor, Faculty of Health Sciences
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Labels

Fields of Research (FoR)

31 Biological Sciences3105 Genetics3001 Agricultural biotechnology3102 Bioinformatics and computational biology

Medical Subject Headings (MeSH)

ADAM ProteinsADAMTS7 ProteinAdultAgedAsian PeopleCase-Control StudiesCoronary Artery DiseaseFemaleGenetic Predisposition to DiseaseGenome-Wide Association StudyHumansLymphokinesMaleMiddle AgedOligonucleotide Array Sequence AnalysisPlatelet-Derived Growth FactorPolymorphism, Single NucleotideQuantitative Trait LociSterol EsteraseTranscription FactorsWhite People
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