Real-Time RT-PCR Allelic Discrimination Assay for Detection of N501Y Mutation in the Spike Protein of SARS-CoV-2 Associated with B.1.1.7 Variant of Concern Journal Articles

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abstract

During the coronavirus disease 2019 (COVID-19) pandemic, several variants of concern (VOCs) have been detected, for example, B.1.1.7, B.1.351, P.1, and B.1.617.2. The VOCs pose a threat to public health efforts to control the spread of the virus.

authors

Abdulnoor, Mariana
Eshaghi, AliReza
Perusini, Stephen J
Broukhanski, George
Corbeil, Antoine
Cronin, Kirby
Fittipaldi, Nahuel
Forbes, Jessica D
Guthrie, Jennifer L
Kus, Julianne V
Li, Ye
Majury, Anna
Mallo, Gustavo V
Mazzulli, Tony
Melano, Roberto G
Olsha, Romy
Sullivan, Ashleigh
Tran, Vanessa
Patel, Samir N
Allen, Vanessa G
Gubbay, Jonathan B

status

published

publication date

February 23, 2022

has subject area

Alleles (MeSH)
Amino Acid Substitution (MeSH)
COVID-19 (MeSH)
Genes, Viral (MeSH)
Humans (MeSH)
Mass Screening (MeSH)
Mutation, Missense (MeSH)
Ontario (MeSH)
Point Mutation (MeSH)
Polymorphism, Single Nucleotide (MeSH)
Population Surveillance (MeSH)
Prevalence (MeSH)
Real-Time Polymerase Chain Reaction (MeSH)
Reproducibility of Results (MeSH)
SARS-CoV-2 (MeSH)
Sensitivity and Specificity (MeSH)
Spike Glycoprotein, Coronavirus (MeSH)

published in

Microbiology spectrum Journal