Journal article
Genome-wide association study of sepsis in extremely premature infants
Abstract
OBJECTIVE: To identify genetic variants associated with sepsis (early-onset and late-onset) using a genome-wide association (GWA) analysis in a cohort of extremely premature infants.
STUDY DESIGN: Previously generated GWA data from the Neonatal Research Network's anonymised genomic database biorepository of extremely premature infants were used for this study. Sepsis was defined as culture-positive early-onset or late-onset sepsis or …
Authors
Srinivasan L; Page G; Kirpalani H; Murray JC; Das A; Higgins RD; Carlo WA; Bell EF; Goldberg RN; Schibler K
Journal
Archives of Disease in Childhood Fetal & Neonatal, Vol. 102, No. 5,
Publisher
BMJ
Publication Date
September 2017
DOI
10.1136/archdischild-2016-311545
ISSN
1359-2998
Fields of Research (FoR)
Sustainable Development Goals (SDG)
Medical Subject Headings (MeSH)
ATP-Binding Cassette TransportersAdaptor Proteins, Signal TransducingCohort StudiesEndopeptidasesFemaleForkhead Transcription FactorsGTPase-Activating ProteinsGenome-Wide Association StudyGenotypeHumansInfant, Extremely PrematureInfant, NewbornIon ChannelsMaleMicrofilament ProteinsPolymorphism, Single NucleotideSepsis