Journal article
Investigation on ERCC5 genetic polymorphisms and the development of gastric cancer in a Chinese population
Abstract
Our study aimed to investigate the role of 2 ERCC5 promoter SNPs (rs2094258 and rs751402) in the development of gastric cancer in the Chinese population. The present hospital-based case-control study consisted of 155 patients with gastric cancer and 246 healthy controls recruited between March 2012 and December 2014. Genotyping for the rs2094258 and rs751402 polymorphic sites was carried out using polymerase chain reaction-restriction fragment …
Authors
Yang LQ; Zhang Y; Sun HF
Journal
Genetics and Molecular Research, Vol. 15, No. 3,
Publisher
Genetics and Molecular Research
DOI
10.4238/gmr.15038364
ISSN
1676-5680
Associated Experts
Fields of Research (FoR)
Medical Subject Headings (MeSH)
AdultAgedAllelesAsian PeopleCase-Control StudiesDNA-Binding ProteinsEndonucleasesFemaleGene ExpressionGene FrequencyGenetic Predisposition to DiseaseHumansLogistic ModelsMaleMiddle AgedNuclear ProteinsOdds RatioPolymerase Chain ReactionPolymorphism, Restriction Fragment LengthPolymorphism, Single NucleotidePromoter Regions, GeneticRiskStomach NeoplasmsTranscription Factors