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Thymic stromal lymphopoietin (TSLP) secretion from...
Journal article

Thymic stromal lymphopoietin (TSLP) secretion from human nasal epithelium is a function of TSLP genotype

Abstract

Recent candidate gene and genome-wide association studies have identified "protective" associations between the single-nucleotide polymorphism (SNP) rs1837253 in the TSLP gene and risk for allergy, asthma, and airway hyperresponsiveness. The absence of linkage disequilibrium of rs1837253 with other SNPs in the region suggests it is likely a causal polymorphism for these associations, having functional consequences. We hypothesized that …

Authors

Hui CCK; Yu A; Heroux D; Akhabir L; Sandford AJ; Neighbour H; Denburg JA

Journal

Mucosal Immunology, Vol. 8, No. 5, pp. 993–999

Publisher

Elsevier

Publication Date

9 2015

DOI

10.1038/mi.2014.126

ISSN

1933-0219