Journal article
Genetic variation in hyaluronan metabolism loci is associated with plasma plasminogen activator inhibitor-1 concentration
Abstract
Elevated plasma plasminogen activator inhibitor-1 (PAI-1) concentration is associated with cardiovascular disease risk. PAI-1 is the primary inhibitor of fibrinolysis within both the circulation and the arterial wall, playing roles in both atherosclerosis and thrombosis. To define the heritable component, subjects within the population-based SHARE (Study of Health Assessment and Risk in Ethnic groups) and SHARE-AP (Study of Health Assessment …
Authors
Lanktree MB; Johansen CT; Anand SS; Davis AD; Miller R; Yusuf S; Hegele RA; behalf of the SHARE AS-AIO
Journal
Blood, Vol. 116, No. 12, pp. 2160–2163
Publisher
American Society of Hematology
Publication Date
September 23, 2010
DOI
10.1182/blood-2010-02-269902
ISSN
0006-4971