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Impact of a Genetic Risk Score on Myocardial...
Journal article

Impact of a Genetic Risk Score on Myocardial Infarction Risk Across Different Ethnic Populations

Abstract

BACKGROUND: Myocardial infarction (MI) risk varies by ethnicity, although the influence of genetic factors remains unclear. Using a genetic risk score (GRS), we examined the association between 25 coronary artery disease (CAD)-related single nucleotide polymorphisms and MI across 6 ethnic groups. METHODS: We studied 8556 participants in the INTERHEART case-control study from 6 ethnic groups: Europeans, South Asians, Southeast Asians, Arabs, …

Authors

Joseph PG; Pare G; Asma S; Engert JC; Yusuf S; Anand SS; Investigators I

Journal

Canadian Journal of Cardiology, Vol. 32, No. 12, pp. 1440–1446

Publisher

Elsevier

Publication Date

12 2016

DOI

10.1016/j.cjca.2016.05.014

ISSN

0828-282X