Journal article
Blood CSF1 and CXCL12 as Causal Mediators of Coronary Artery Disease
Abstract
BACKGROUND: Identification of biomarkers that cause coronary artery disease (CAD) has led to important advances in prevention and treatment. Epidemiological analyses have identified many biomarker-CAD relationships; however, these associations may arise from reverse causation and/or confounding and therefore may not represent true causal associations. Mendelian randomization (MR) analyses overcome these limitations.
OBJECTIVES: This study …
Authors
Sjaarda J; Gerstein H; Chong M; Yusuf S; Meyre D; Anand SS; Hess S; Paré G
Journal
Journal of the American College of Cardiology, Vol. 72, No. 3, pp. 300–310
Publisher
Elsevier
Publication Date
7 2018
DOI
10.1016/j.jacc.2018.04.067
ISSN
0735-1097