Journal article
The Effect of Chromosome 9p21 Variants on Cardiovascular Disease May Be Modified by Dietary Intake: Evidence from a Case/Control and a Prospective Study
Abstract
BACKGROUND: One of the most robust genetic associations for cardiovascular disease (CVD) is the Chromosome 9p21 region. However, the interaction of this locus with environmental factors has not been extensively explored. We investigated the association of 9p21 with myocardial infarction (MI) in individuals of different ethnicities, and tested for an interaction with environmental factors.
METHODS AND FINDINGS: We genotyped four 9p21 SNPs in …
Authors
Do R; Xie C; Zhang X; Männistö S; Harald K; Islam S; Bailey SD; Rangarajan S; McQueen MJ; Diaz R
Journal
PLOS Medicine, Vol. 8, No. 10,
Publisher
Public Library of Science (PLoS)
Publication Date
10 2011
DOI
10.1371/journal.pmed.1001106
ISSN
1549-1277