Recombinant Proteins Concept

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• 1976 and 2009 H1N1 Influenza Virus Vaccines Boost Anti-Hemagglutinin Stalk Antibodies in Humans  Journal Articles
• 6 Mechanism of action of the thrombolytic agents  Journal Articles
• Chlamydophila pneumoniae PknD Exhibits Dual Amino Acid Specificity and Phosphorylates Cpn0712, a Putative Type III Secretion YscD Homolog  Journal Articles
• Escherichia coliHeat-Labile Enterotoxin B Subunit Is a More Potent Mucosal Adjuvant than Its Closely Related Homologue, the B Subunit of Cholera Toxin  Journal Articles
• Escherichia coliShiga toxins induce apoptosis in epithelial cells that is regulated by the Bcl-2 family  Journal Articles
• In VivoClearance of Alpha-1 Acid Glycoprotein Is Influenced by the Extent of Its N-Linked Glycosylation and by Its Interaction with the Vessel Wall  Journal Articles
• Staphylococcus aureus Fibronectin-Binding Protein Serves as a Substrate for Coagulation Factor XIIIa:  Evidence for Factor XIIIa-Catalyzed Covalent Cross-Linking to Fibronectin and Fibrin  Journal Articles
• d -Ala- d -Ala ligases from glycopeptide antibiotic-producing organisms are highly homologous to the enterococcal vancomycin-resistance ligases VanA and VanB  Journal Articles
• l-Hydroxyproline andd-Proline Catabolism in Sinorhizobium meliloti  Journal Articles
• A Control Switch for Prothrombinase  Journal Articles
• A Detailed Comparison of the Performance of the Standard versus the Nijmegen Modification of the Bethesda Assay in Detecting Factor VIII:C Inhibitors in the Haemophilia A Population of Canada  Journal Articles
• A Historical Perspective on the Reversal of Anticoagulants  Journal Articles
• A Mechanism for the Auto-inhibition of Hyperpolarization-activated Cyclic Nucleotide-gated (HCN) Channel Opening and Its Relief by cAMP  Journal Articles
• A Multicenter Study of Recombinant Factor VIII (RecombinateTM) in Previously Treated Patients with Hemophilia A  Journal Articles
• A New Short Infusion Dosage Regimen of Recombinant Tissue Plasminogen Activator in Patients with Venous Thromboembolic Disease  Journal Articles
• A PoTENtial Antidote  Journal Articles
• A Prospective Randomized Study of Alpha-2b Interferon plus Hydroxyurea or Cytarabine for Patients with Early Chronic Phase Chronic Myelogenous Leukemia: The International Oncology Study Group CML1 Study  Journal Articles
• A Prospective, non-randomised phase 1–2 trial of VACOP-B with filgrastim support for HIV-related non-Hodgkin's lymphoma  Journal Articles
• A Randomized Trial of a Single Bolus Dosage Regimen of Recombinant Tissue Plasminogen Activator in Patients with Acute Pulmonary Embolism  Journal Articles
• A Randomized, Double-Blind, Placebo-Controlled, Phase 2b Study to Evaluate the Safety and Efficacy of Recombinant Human Soluble Thrombomodulin, ART-123, in Patients With Sepsis and Suspected Disseminated Intravascular Coagulation*  Journal Articles
• A Role of p73 in Mitotic Exit  Journal Articles
• A Single Point Mutation in ϵ-COP Results in Temperature-sensitive, Lethal Defects in Membrane Transport in a Chinese Hamster Ovary Cell Mutant  Journal Articles
• A Small-Molecule Inhibitor of Bax and Bak Oligomerization Prevents Genotoxic Cell Death and Promotes Neuroprotection  Journal Articles
• A Thermal-Cycling Method for Disaggregating Monoclonal Antibody Oligomers  Journal Articles
• A barbed end interference mechanism reveals how capping protein promotes nucleation in branched actin networks  Journal Articles
• A covalently linked recombinant albumin dimer is more rapidly cleared in vivo than are wild-type and mutant C34A albumin  Journal Articles
• A cytosolic herpes simplex virus protein inhibits antigen presentation to CD8+ T lymphocytes  Journal Articles
• A fast, efficient, and scalable method for purifying recombinant SARS-CoV-2 spike protein  Journal Articles
• A functionally divergent hydrogenosomal peptidase with protomitochondrial ancestry  Journal Articles
• A glycosyl hydrolase activity of mammalian reovirus σ1 protein can contribute to viral infection through a mucus layer 1 1Edited by M. Yaniv  Journal Articles
• A long-term follow-up study investigating health-related quality of life and resource use in survivors of severe sepsis: comparison of recombinant human activated protein C with standard care  Journal Articles
• A multicentre, randomised trial comparing schedules of G-CSF (filgrastim) administration for primary prophylaxis of chemotherapy-induced febrile neutropenia in early stage breast cancer  Journal Articles
• A p56 Ligand Serves as a Coactivator of an Orphan Nuclear Hormone Receptor  Journal Articles
• A phase 2 PK/PD study of andexanet alfa for reversal of rivaroxaban and edoxaban anticoagulation in healthy volunteers  Journal Articles
• A plasmin-activatable thrombin inhibitor reduces experimental thrombosis and assists experimental thrombolysis in murine models  Journal Articles
• A preliminary study on the usefulness of huil-8 in cervical relaxation of the ewe for artificial insemination and for embryo transfer  Journal Articles
• A randomized study of alpha‐interferon plus ribavirin for 6 months or 12 months for the treatment of chronic hepatitis C in patients with bleeding disorders  Journal Articles
• A role for mucosal IL-22 production and Th22 cells in HIV-associated mucosal immunopathogenesis  Journal Articles
• A safety review of topical bovine thrombin-induced generation of antibodies to bovine proteins  Journal Articles
• A therapeutic alternative for haemophiliacs with inhibitors  Journal Articles
• ATM activity contributes to the tumor-suppressing functions of p14ARF  Journal Articles
• Activated Protein C Up-Regulates IL-10 and Inhibits Tissue Factor in Blood Monocytes  Journal Articles
• Activated protein C improves intestinal microcirculation in experimental endotoxaemia in the rat.  Journal Articles
• Activated protein C modulates inflammation, apoptosis and tissue factor procoagulant activity by regulating endoplasmic reticulum calcium depletion in blood monocytes  Journal Articles
• Activation and Active Site Occupation Alter Conformation in the Region of the First Epidermal Growth Factor-like Domain of Human Factor VII  Journal Articles
• Activin and transforming growth factor-β as local regulators of ovarian steroidogenesis in the goldfish  Journal Articles
• Acute Hypoxic Regulation of Recombinant THIK-1 Stably Expressed in HEK293 Cells  Journal Articles
• Adaptive immune responses fail to provide protection against genital HSV‐2 infection in the absence of IL‐15  Journal Articles
• Adenoviral Transfer of Murine Oncostatin M Elicits Periosteal Bone Apposition in Knee Joints of Mice, Despite Synovial Inflammation and Up-Regulated Expression of Interleukin-6 and Receptor Activator of Nuclear Factor-κB Ligand  Journal Articles
• Adenoviral Transfer of the Murine Oncostatin M Gene Suppresses Dextran-Sodium Sulfate-Induced Colitis  Journal Articles
• Adenoviral-Mediated Gene Transfer into Bone Marrow: An Effective Surgical Technique in Rat  Journal Articles
• Adenovirus Vector Expressing Mouse Oncostatin M Induces Acute-Phase Proteins and TIMP-1 ExpressionIn Vivoin Mice  Journal Articles
• Adenovirus Vectors for Cytokine Gene Expression  Conferences
• Adenovirus-Mediated Interleukin-10 Gene Transfer Inhibits Post-Transplant Fibrous Airway Obliteration in an Animal Model of Bronchiolitis Obliterans  Journal Articles
• Adenovirus-mediated gene transfer of the tumor suppressor, p53, induces apoptosis in postmitotic neurons.  Journal Articles
• Adenoviruses as expression vectors and recombinant vaccines  Journal Articles
• Advances in Antithrombotic Therapy: Novel Agents  Journal Articles
• Affinity Purification and Elimination of Methionine Oxidation in Recombinant Human Cystatin C  Journal Articles
• Allosteric Site Variants of Haemophilus influenzae β-Carbonic Anhydrase  Journal Articles
• Alternative outcomes for the multiple breath washout in children with CF  Journal Articles
• American Society of Hematology 2018 guidelines for management of venous thromboembolism: heparin-induced thrombocytopenia  Journal Articles
• Amphiphysin is a component of clathrin coats formed during synaptic vesicle recycling at the lamprey giant synapse.  Journal Articles
• Amyloid protein precursor stimulates excitatory amino acid transport. Implications for roles in neuroprotection and pathogenesis.  Journal Articles
• An Automated Micro-Total Immunoassay System for Measuring Cancer-Associated α2,3-linked Sialyl N-Glycan-Carrying Prostate-Specific Antigen May Improve the Accuracy of Prostate Cancer Diagnosis  Journal Articles
• An In Vitro Screen of Bacterial Lipopolysaccharide Biosynthetic Enzymes Identifies an Inhibitor of ADP-Heptose Biosynthesis  Journal Articles
• An illustrative case and a review on the dosing of recombinant factor VIIa in congenital factor XI deficiency  Journal Articles
• An important role for the activation peptide domain in controlling factor IX levels in the blood of haemophilia B mice  Conferences
• An omics approach to rational feed: Enhancing growth in CHO cultures with NMR metabolomics and 2D-DIGE proteomics. - PubMed - NCBI  Journal Articles
• An unconventional strategy for purifying recombinant SARS-CoV-2 spike protein.  Journal Articles
• An unusual eukaryotic protein phosphatase required for transcription by RNA polymerase II and CTD dephosphorylation in S. cerevisiae.  Journal Articles
• Analysis of Prostaglandin G/H Synthase-2 Inhibition Using Peroxidase-Induced Luminol Luminescence  Journal Articles
• Analysis of the cost effectiveness of recombinant versus urinary follicle-stimulating hormone in in vitro fertilization/intracytoplasmic sperm injection programs in the United States  Conferences
• Andexanet Alfa for Acute Major Bleeding Associated with Factor Xa Inhibitors  Journal Articles
• Andexanet Alfa for Reversal of Factor Xa Inhibitors: A Critical Review of the Evidence  Journal Articles
• Andexanet Alfa for Specific Anticoagulation Reversal in Patients with Acute Bleeding during Treatment with Edoxaban  Journal Articles
• Andexanet Alfa for the Reversal of Factor Xa Inhibitor Activity  Journal Articles
• Andexanet alfa for the treatment of hemorrhage  Journal Articles
• Andexanet alfa versus four-factor prothrombin complex concentrate for the reversal of apixaban- or rivaroxaban-associated intracranial hemorrhage: a propensity score-overlap weighted analysis  Journal Articles
• Andexanet alfa versus non-specific treatments for intracerebral hemorrhage in patients taking factor Xa inhibitors — Individual patient data analysis of ANNEXA-4 and TICH-NOAC  Journal Articles
• Andexanet for Factor Xa Inhibitor-Associated Acute Intracerebral Hemorrhage. Reply.  Journal Articles
• Andexanet for Factor Xa Inhibitor–Associated Acute Intracerebral Hemorrhage  Journal Articles
• Antibodies to rat soluble IL‐6 receptor stimulate B9 hybridoma cell proliferation  Journal Articles
• Antibody-modified conduits for highly selective cytokine elimination from blood  Journal Articles
• Anticoagulants in acute coronary syndromes  Journal Articles
• Anticoagulation for cardiopulmonary bypass: Is a replacement for heparin on the horizon?  Journal Articles
• Antithrombin alfa in hereditary antithrombin deficient patients: A phase 3 study of prophylactic intravenous administration in high risk situations  Journal Articles
• Antithrombotic Therapy During Percutaneous Coronary Intervention  Journal Articles
• Antithrombotic and thrombolytic therapy for ischemic stroke: antithrombotic therapy and prevention of thrombosis: American College of Chest Physicians Evidence-Based Clinical Practice Guidelines  Journal Articles
• Antiviral treatment for chronic hepatitis C in patients with human immunodeficiency virus  Journal Articles
• Assessing the Value of a New Pharmaceutical  Journal Articles
• Assessment of Requirements for IL-15 and IFN Regulatory Factors in Uterine NK Cell Differentiation and Function During Pregnancy  Journal Articles
• Association between recombinant human erythropoietin and quality of life and exercise capacity of patients receiving haemodialysis. Canadian Erythropoietin Study Group.  Journal Articles
• Atrazine‐induced changes in aromatase activity in estrogen sensitive target tissues  Journal Articles
• Autoantibodies against the cell surface–associated chaperone GRP78 stimulate tumor growth via tissue factor  Journal Articles
• Autoimmune heparin‐induced thrombocytopenia and venous limb gangrene after aortic dissection repair: in vitro and in vivo effects of intravenous immunoglobulin  Journal Articles
• BDNF and PDE4, but not the GRPR, Regulate Viability of Human Medulloblastoma Cells  Journal Articles
• BDNF/TrkB Content and Interaction with Gastrin-Releasing Peptide Receptor Blockade in Colorectal Cancer  Journal Articles
• Bcl-XL is qualitatively different from and ten times more effective than Bcl-2 when expressed in a breast cancer cell line  Journal Articles
• Beneficial Effects of Extended Growth Hormone Treatment After Hospital Discharge in Pediatric Burn Patients  Journal Articles
• Beyond Heparin and Aspirin  Journal Articles
• Beyond Unfractionated Heparin and Warfarin  Journal Articles
• Bioavailability of Iron in Hemodialysis Patients Treated With Erythropoietin: Evidence for the Inhibitory Role of Aluminum  Journal Articles
• Biochemical and pharmacological profile of a tetrasubstituted furanone as a highly selective COX‐2 inhibitor  Journal Articles
• Biodistribution of covalent antithrombin-heparin complexes  Journal Articles
• Biosimilars for psoriasis: preclinical analytical assessment to determine similarity  Journal Articles
• Bivalent direct thrombin inhibitors: hirudin and bivalirudin  Journal Articles
• Bivalirudin  Journal Articles
• Bivalirudin in patients with heparin-induced thrombocytopenia undergoing percutaneous coronary intervention.  Journal Articles
• Bivalirudin versus Unfractionated Heparin during Percutaneous Coronary Intervention in Patients with Non‐ST‐Segment Elevation Acute Coronary Syndrome Initially Treated with Fondaparinux: Results from an International, Multicenter, Randomized Pilot Study (SWITCH III)  Journal Articles
• Bivalirudin, thrombin and platelets: clinical implications and future directions.  Journal Articles
• Bivalirudin: a review  Journal Articles
• Bleeding Complications and Management on anticoagulant therapy  Journal Articles
• Broad Spectrum Aminoglycoside Phosphotransferase Type III from Enterococcus: Overexpression, Purification, and Substrate Specificity  Journal Articles
• CD11c/CD18 on neutrophils recognizes a domain at the N terminus of the A alpha chain of fibrinogen.  Journal Articles
• CENTRAL INTERLEUKIN-1 RECEPTORS CONTRIBUTE TO SUPPRESSION OF FEEDING AFTER ACUTE COLITIS IN THE RAT  Journal Articles
• CNTF is superior to NGF as a survival enhancement factor for adrenal medulla cells in vitro  Journal Articles
• CYB5D2 enhances HeLa cells survival of etoposide-induced cytotoxicity  Journal Articles
• Ca2+ and Zn2+ binding properties of peptide substrates of vertebrate collagenase, MMP-1  Journal Articles
• Can activated recombinant factor VII be used to postpone the exposure of infants to factor VIII until after 2 years of age?  Journal Articles
• Cardiac surgery in patients with haemophilia B: a case report and review of the literature  Journal Articles
• Cell‐free protein synthesis and purification of human dopamine D2 receptor long isoform  Journal Articles
• Central interleukin-1 receptors contribute to suppression of feeding after acute colitis in the rat  Journal Articles
• Cerebral hemorrhage after intra-arterial thrombolysis for ischemic stroke  Journal Articles
• Characterization and Biologic Activities of Recombinant Rat Soluble Interleukin-6 Receptor  Journal Articles
• Characterization and IL-15 dependence of NK cells in humanized mice  Journal Articles
• Characterization of CHO-K1 cells stably expressing PDE-IV enzymes  Journal Articles
• Characterization of full-length recombinant human Proteoglycan 4 as an ocular surface boundary lubricant  Journal Articles
• Characterization of the Putative Type III Secretion ATPase CdsN (Cpn0707) ofChlamydophila pneumoniae  Journal Articles
• Characterization of the Shope Fibroma Virus DNA Ligase Gene  Journal Articles
• Chicken ovalbumin upstream promoter transcription factor (COUP-TF) binds to a peroxisome proliferator-responsive element and antagonizes peroxisome proliferator-mediated signaling.  Journal Articles
• Chronic Exposure to Innocuous Antigen in Sensitized Mice Leads to Suppressed Airway Eosinophilia That Is Reversed by Granulocyte Macrophage Colony-Stimulating Factor  Journal Articles
• Cleavage-dependent Ligation by the FLP Recombinase  Journal Articles
• Clinical Implications of Reversal Agents for Direct Oral Anticoagulants  Journal Articles
• Clinical outcomes in relation to the daily dose of recombinant follicle-stimulating hormone for ovarian stimulation in in vitro fertilization in presumed normal responders younger than 39 years: a meta-analysis  Journal Articles
• Clinical trial: exposure to ribavirin predicts EVR and SVR in patients with HCV genotype 1 infection treated with peginterferon alfa‐2a plus ribavirin  Journal Articles
• Cloning and Characterization of Oxidosqualene Cyclases from Kalanchoe daigremontiana  Journal Articles
• Cloning, characterization, and functional studies of a human 40-kDa catecholamine-regulated protein: implications in central nervous system disorders  Journal Articles
• Cloning, expression and chromosomal mapping of human lysosomal sialidase and characterization of mutations in sialidosis  Journal Articles
• Combination 13-cis-retinoic acid and interferon alpha-2a in the therapy of solid tumors.  Journal Articles
• Combination 13-cis-retinoic acid and interferon alpha-2a in the therapy of solid tumors.  Journal Articles
• Combination of recombinant human growth hormone and propranolol decreases hypermetabolism and inflammation in severely burned children*  Journal Articles
• Combined Immunotherapy and Antiangiogenic Therapy of Cancer with Microencapsulated Cells  Journal Articles
• Comment: Treatment of Heparin-Induced Thrombocytopenia  Journal Articles
• Comparative evaluation of IGF-I gene transfer and IGF-I protein administration for enhancing skeletal muscle regeneration after injury  Journal Articles
• Comparing bleed frequency and factor concentrate use between haemophilia A and B patients  Journal Articles
• Comparison of Heparin- and Dermatan Sulfate-mediated Catalysis of Thrombin Inactivation by Heparin Cofactor II  Journal Articles
• Comparison of Subcutaneous and Intravenous Recombinant Human Erythropoietin for Anemia in Hemodialysis Patients with Significant Comorbid Disease  Journal Articles
• Comparison of bivalirudin versus heparin during percutaneous coronary intervention (the Randomized Evaluation of PCI Linking Angiomax to Reduced Clinical Events [REPLACE]-1 trial)  Journal Articles
• Comparison of mammalian and bacterial expression library screening to detect recombinant alpha-1 proteinase inhibitor variants with enhanced thrombin inhibitory capacity☆  Journal Articles
• Comparison of recombinant and plasma-derived antithrombin biodistribution in a rabbit model  Journal Articles
• Comparison of the Effects of Two Doses of Recombinant Hirudin Compared With Heparin in Patients With Acute Myocardial Ischemia Without ST Elevation  Journal Articles
• Comprehensive Canadian Review of the Off-Label Use of Recombinant Activated Factor VII in Cardiac Surgery  Journal Articles
• Conserved inserts in the Hsp60 (GroEL) and Hsp70 (DnaK) proteins are essential for cellular growth  Journal Articles
• Construction and Characterization of a Replication-Deficient Adenovirus Expressing Rat-Soluble Interleukin-6 Receptor  Journal Articles
• Construction of a recombinant adenovirus for efficient delivery of the I-Scel yeast endonuclease to human cells and its application in the in vivo cleavage of chromosomes to expose new potential telomeres  Journal Articles
• Construction of recombinant human type 5 adenoviruses expressing rodent IL-6 genes. An approach to investigate in vivo cytokine function.  Journal Articles
• Construction, function and in vivo expression of a complement receptor type 1 containing recombinant adenovirus for use in xenotransplantation  Conferences
• Continuing Challenges of Sepsis Research  Journal Articles
• Continuous Infusion of Recombinant Factor VIIa in Hemophilic Patients with Inhibitors: Safety, Monitoring, and Cost Effectiveness  Journal Articles
• Continuous epidermal growth factor delivery in corneal epithelial wound healing.  Journal Articles
• Continuous infusion of recombinant factor VIIa for surgery in patients with deficiency of factor VII  Journal Articles
• Continuous intravenous infusion of a plasma‐derived factor IX concentrate (Mononine^®) in haemophilia B  Journal Articles
• Continuous prophylaxis with recombinant factor IX Fc fusion protein and conventional recombinant factor IX products: comparisons of efficacy and weekly factor consumption  Journal Articles
• Conveying and discussing uncertainty— looking in both directions  Journal Articles
• Correction of the Growth Defect in Dwarf Mice with Nonautologous Microencapsulated Myoblasts—An Alternate Approach to Somatic Gene Therapy  Journal Articles
• Cost-effectiveness modelling of recombinant FSH versus urinary FSH in assisted reproduction techniques in the UK  Journal Articles
• Cost-effectiveness of a Transplantation Strategy Compared to Melphalan and Prednisone in Younger Patients with Multiple Myeloma  Journal Articles
• Cost-effectiveness of recombinant versus urinary follicle-stimulating hormone in assisted reproduction techniques in the Spanish public health care system.  Journal Articles
• Costimulatory ligand 4-1BBL (CD137L) as an efficient adjuvant for human antiviral cytotoxic T cell responses  Journal Articles
• Costs Associated with Erythropoiesis-Stimulating Agent Administration to Hemodialysis Patients  Journal Articles
• Cowden Syndrome–Affected Patients with PTEN Promoter Mutations Demonstrate Abnormal Protein Translation  Journal Articles
• Crystal Structure of a Ca2+-discharged Photoprotein  Journal Articles
• Crystallization and preliminary X-ray diffraction studies of glycerol 3-phosphate cytidylyltransferase fromStaphylococcus aureus  Journal Articles
• Crystallization and preliminary X-ray diffraction studies of homoserine dehydrogenase from Saccharomyces cerevisiae  Journal Articles
• Crystallization of Bacillus subtilis Tryptophanyl-tRNA Synthetase  Journal Articles
• Culture and Isolation of Brain Tumor Initiating Cells  Journal Articles
• Current agents for the treatment of patients with heparin-induced thrombocytopenia  Journal Articles
• Current use of biologicals in thrombosis and haemostasis  Journal Articles
• D-TACC: a novel centrosomal protein required for normal spindle function in the early Drosophila embryo.  Journal Articles
• Degradation of proteoglycan 4/lubricin by cathepsin S: Potential mechanism for diminished ocular surface lubrication in Sjögren's syndrome  Journal Articles
• Deletion mutagenesis of heparin cofactor II: defining the minimum size of a thrombin inhibiting serpin  Journal Articles
• Delivery of Recombinant Gene Product to Canines with Nonautologous Microencapsulated Cells  Journal Articles
• Delivery of Recombinant Gene Products with Microencapsulated Cells In Vivo  Journal Articles
• Delivery of recombinant gene product to canine brain with the use of microencapsulation  Journal Articles
• Demonstration of a splenic cytotoxic effector cell in mice of genotype SCID/SCID.BG/BG  Journal Articles
• Design, baseline characteristics, and preliminary clinical results of the Organization to Assess Strategies for Ischemic Syndromes–2 (OASIS–2) trial  Journal Articles
• Development and Validation of a Population-Pharmacokinetic Model for Rurioctacog Alfa Pegol (Adynovate®): A Report on Behalf of the WAPPS-Hemo Investigators Ad Hoc Subgroup  Journal Articles
• Development of a bovine adenovirus type 3-based expression vector  Journal Articles
• Development of a helper-independent human adenovirus vector and its use in the transfer of the herpes simplex virus thymidine kinase gene  Journal Articles
• Development of a high-yield expression and purification system for platelet factor 4  Journal Articles
• Dialysis patients treated with Epoetin alfa show improved anemia symptoms: A new analysis of the Canadian Erythropoietin Study Group trial  Journal Articles
• Differences in the clinically effective molar concentrations of four direct thrombin inhibitors explain their variable prothrombin time prolongation  Journal Articles
• Different preparations of natural and recombinant human interleukin-6 (ifn-β2, bsf-2) similarly stimulate acute phase protein synthesis and uptake of α-aminoisobutyric acid by cultured rat hepatocytes  Journal Articles
• Differentiation of neural stem cells in three-dimensional growth factor-immobilized chitosan hydrogel scaffolds  Journal Articles
• Direct Oral Anticoagulant- or Warfarin-Related Major Bleeding  Journal Articles
• Direct Thrombin Inhibitors  Conferences
• Direct Thrombin Inhibitors in Cardiac Disease  Journal Articles
• Direct comparison of two extended half-life PEGylated recombinant FVIII products: a randomized, crossover pharmacokinetic study in patients with severe hemophilia A  Journal Articles
• Direct thrombin inhibitors for treatment of arterial thrombosis: potential differences between bivalirudin and hirudin  Conferences
• Direct thrombin inhibitors in acute coronary syndromes  Journal Articles
• Direct thrombin inhibitors in acute coronary syndromes: principal results of a meta-analysis based on individual patients' data  Journal Articles
• Direct-acting antiviral therapies for hepatitis C genotype 1 infection: a multiple treatment comparison meta-analysis  Journal Articles
• Discovery of a novel class of aldol-derived 1,2,3-triazoles: Potent and selective inhibitors of human cytochrome P450 19A1 (aromatase)  Journal Articles
• Disparate Subcellular Localization Patterns of Pseudomonas aeruginosa Type IV Pilus ATPases Involved in Twitching Motility  Journal Articles
• Displacement of Fibrin-bound Thrombin by r-Hirudin Precludes the Use of 131l-r-Hirudin for Detecting Pulmonary Emboli in the Rabbit  Journal Articles
• Disruption of antigen-induced inflammatory responses in CD40 ligand knockout mice.  Journal Articles
• Disseminated Langerhans Cell Histiocytosis in Identical Twins Unresponsive to Recombinant Human α-Interferon and Total Body Irradiation  Journal Articles
• Distinct lipid effects on tBid and Bim activation of membrane permeabilization by pro-apoptotic Bax  Journal Articles
• Distinct sets of acute phase plasma proteins are stimulated by separate human hepatocyte-stimulating factors and monokines in rat hepatoma cells.  Journal Articles
• Distinguishing West Nile virus infection using a recombinant envelope protein with mutations in the conserved fusion-loop  Journal Articles
• Dose–response study of recombinant human soluble thrombomodulin (ART‐123) in the prevention of venous thromboembolism after total hip replacement  Journal Articles
• Drotrecogin alfa (activated) in patients with severe sepsis and a high risk of death.  Journal Articles
• Drotrecogin alfa (activated): does current evidence support treatment for any patients with severe sepsis?  Journal Articles
• Drotrecogin alfa (activated): down and not out, but not really in either.  Journal Articles
• Dynamic unfolding of a regulatory subunit of cAMP‐dependent protein kinase by capillary electrophoresis: Impact of cAMP dissociation on protein stability  Journal Articles
• Dynamin Interacts with Members of the Sumoylation Machinery  Journal Articles
• Economic analysis of epoetin alfa in critically ill trauma patients  Journal Articles
• Efanesoctocog Alfa Prophylaxis for Children with Severe Hemophilia A  Journal Articles
• Effect of FKBP65, a putative elastin chaperone, on the coacervation of tropoelastin in vitro  Journal Articles
• Effect of GM-CSF on immune, inflammatory, and clinical responses to ragweed in a novel mouse model of mucosal sensitization  Journal Articles
• Effect of Leptin on Vascular Calcification in Apolipoprotein E–Deficient Mice  Journal Articles
• Effect of Recombinant Human Erythropoietin Therapy on Blood Pressure in Hemodialysis Patients  Journal Articles
• Effect of a Recombinant Human Soluble Thrombomodulin on Mortality in Patients With Sepsis-Associated Coagulopathy  Journal Articles
• Effect of chronic kidney disease on red blood cell rheology.  Journal Articles
• Effect of recombinant factor VIIa on melagatran-induced inhibition of thrombin generation and platelet activation in healthy volunteers  Journal Articles
• Effect of recombinant human erythropoietin on hospitalization of hemodialysis patients.  Journal Articles
• Effectiveness and safety of abciximab after failed thrombolytic therapy  Journal Articles
• Effectiveness of Intrapleural Tissue Plasminogen Activator and Dornase Alfa vs Tissue Plasminogen Activator Alone in Children with Pleural Empyema  Journal Articles
• Effects in the use of a genetically engineered strain ofLactococcus lactisdelivering in situ IL-10 as a therapy to treat low-grade colon inflammation  Journal Articles
• Effects of Decidual Cell Supernatants and Lymphokines on Murine Trophoblast Growth in Vitro1  Journal Articles
• Effects of Intravenously Administered Recombinant Vesicular Stomatitis Virus (VSV ΔM51 ) on Multifocal and Invasive Gliomas  Journal Articles
• Effects of life-time exposure to waterborne copper on the somatotropic axis of the viviparous fish Poecilia vivipara  Journal Articles
• Effects of recombinant hirudin (lepirudin) compared with heparin on death, myocardial infarction, refractory angina, and revascularisation procedures in patients with acute myocardial ischaemia without ST elevation: a randomised trial  Journal Articles
• Effects of recombinant human interleukin-12 on eosinophils, airway hyper-responsiveness, and the late asthmatic response  Journal Articles
• Effects on Thrombin Generation of Single Injections of Hirulog™ in Patients with Calf Vein Thrombosis  Journal Articles
• Efficacy and Safety of Pegylated Interferon Alfa-2a or Alfa-2b Plus Ribavirin for the Treatment of Chronic Hepatitis C in Children and Adolescents: A Systematic Review and Meta-analysis  Journal Articles
• Efficacy and Safety of Recombinant Human Bone Morphogenetic Protein-2/Calcium Phosphate Matrix for Closed Tibial Diaphyseal Fracture  Journal Articles
• Elevated plasma matrix metalloproteinases and their tissue inhibitors in patients with severe sepsis  Journal Articles
• Encapsulation for Somatic Gene Therapy  Conferences
• Encapsulation of various recombinant mammalian cell types in different alginate microcapsules  Journal Articles
• Engineered Nanoparticle Applications for Recombinant Influenza Vaccines  Journal Articles
• Enhanced activation of cellular AMPK by dual-small molecule treatment: AICAR and A769662  Journal Articles
• Enhanced cell‐free transcription of the ribosomal protein L₃₂ gene by the polyoma virus enhancer PEA3 DNA‐binding protein  Journal Articles
• Eosinophil activation in the tissue: synthetic steroid, budesonide, effectively inhibits the survival of eosinophils isolated from peripheral blood but not nasal polyp tissues.  Journal Articles
• Epitope mapping of inhibitory antibodies targeting the C2 domain of coagulation factor VIII by hydrogen–deuterium exchange mass spectrometry  Journal Articles
• Epoetin Alfa in Cancer Patients  Journal Articles
• Erythropoietin to Prevent Transfusions in Premature Infants  Journal Articles
• Erythropoietin with Iron Supplementation To Prevent Allogeneic Blood Transfusion in Total Hip Joint Arthroplasty  Journal Articles
• Establishing a relationship between prolactin and altered fatty acid β-Oxidation via carnitine palmitoyl transferase 1 in breast cancer cells  Journal Articles
• Establishing the Principles of Recognition in the Adenine-Binding Region of an Aminoglycoside Antibiotic Kinase [APH(3‘)-IIIa]  Journal Articles
• Etoricoxib (MK-0663): preclinical profile and comparison with other agents that selectively inhibit cyclooxygenase-2.  Journal Articles
• Experiences with continuous infusion of recombinant activated factor VII.  Conferences
• Expression in Escherichiacoli of functional precursor to the rat liver mitochondrial enzyme, ornithine carbamyl transferase. Precursor import and processing in vitro  Journal Articles
• Expression of Human 60-kD Heat Shock Protein (HSP60 or P1) inEscherichia coliand the Development and Characterization of Corresponding Monoclonal Antibodies  Journal Articles
• Expression of recombinant human casein kinase II and recombinant heat shock protein 90 in Escherichia coli and characterization of their interactions.  Journal Articles
• Expression screening of bacterial libraries of recombinant alpha-1 proteinase inhibitor variants for candidates with thrombin inhibitory capacity  Journal Articles
• Extracellular Expression, Purification, and Characterization of a Winter Flounder Antifreeze Polypeptide from Escherichia coli  Journal Articles
• Factor IX pharmacokinetics: differences between plasma‐derived and recombinant products and the clinical and economic implications: a meeting report  Conferences
• Factor VIIa gets even bigger  Journal Articles
• Factors Influencing Basophilic Differentiation of HL-60 Cells  Journal Articles
• Feasibility of Using Recombinant Factor VIIa in Continuous Infusion  Journal Articles
• Fibrinogenolysis and thrombin generation after reduced dose bolus or conventional rt-PA for pulmonary embolism. The Coagulation Project Investigators of the Bolus Alteplase Pulmonary Embolism Group.  Journal Articles
• Final Results of the RHAPSODY Trial: A Multi‐Center, Phase 2 Trial Using a Continual Reassessment Method to Determine the Safety and Tolerability of 3K3A‐APC, A Recombinant Variant of Human Activated Protein C, in Combination with Tissue Plasminogen Activator, Mechanical Thrombectomy or both in Moderate to Severe Acute Ischemic Stroke  Journal Articles
• Final Study Report of Andexanet Alfa for Major Bleeding With Factor Xa Inhibitors  Journal Articles
• Fondaparinux versus direct thrombin inhibitor therapy for the management of heparin-induced thrombocytopenia (HIT) – Bridging the River Coumarin  Journal Articles
• Foreign Gene Expression by Human Adenovirus Type 5-Based Vectors Studied Using Firefly Luciferase and Bacterial β-Galactosidase Genes as Reporters  Journal Articles
• Formation and Hematopoietic Differentiation of Human Embryoid Bodies by Suspension and Hanging Drop Cultures  Journal Articles
• Full Study Report of Andexanet Alfa for Bleeding Associated with Factor Xa Inhibitors  Journal Articles
• Full or Partial Substitution of the Reactive Center Loop of α-1-Proteinase Inhibitor by that of Heparin Cofactor II:  P1 Arg Is Required for Maximal Thrombin Inhibition  Journal Articles
• Functional annotation of putative aminoglycoside antibiotic modifying proteins in Mycobacterium tuberculosis H37Rv  Journal Articles
• Functional differences in the cytochrome P450 1 family enzymes from Zebrafish (Danio rerio) using heterologously expressed proteins  Journal Articles
• Functional rescue of vitamin C synthesis deficiency in human cells using adenoviral-based expression of murine l-gulono-γ-lactone oxidase  Journal Articles
• G Protein-coupled Receptor Kinase-mediated Desensitization of Metabotropic Glutamate Receptor 1A Protects against Cell Death  Journal Articles
• GM-CSF Transgene-Based Adjuvant Allows the Establishment of Protective Mucosal Immunity Following Vaccination with Inactivated Chlamydia trachomatis  Journal Articles
• GRANULOCYTE MACROPHAGE COLONY-STIMULATING FACTOR FOR THE THERAPY OF CYTOMEGALOVIRUS AND GANCICLOVIR-INDUCED LEUKOPENIA IN A RENAL TRANSPLANT RECIPIENT  Journal Articles
• Genomic DNA transfer with a high-capacity adenovirus vector results in improved in vivo gene expression and decreased toxicity  Journal Articles
• Growth Hormone Research Society Workshop Summary: Consensus Guidelines for Recombinant Human Growth Hormone Therapy in Prader-Willi Syndrome  Conferences
• Growth hormone and body composition in children younger than 2 years with Prader-Willi syndrome  Journal Articles
• Growth hormone therapy before and after pediatric renal transplant  Journal Articles
• Haemostatic and replacement therapy in von Willebrand disease  Journal Articles
• Health-related quality of life associated with recombinant human erythropoietin therapy for predialysis chronic renal disease patients  Journal Articles
• Helper-dependent adenoviral vectors mediate therapeutic factor VIII expression for several months with minimal accompanying toxicity in a canine model of severe hemophilia A  Journal Articles
• Hemophilia and von Willebrand's disease: 2. Management. Association of Hemophilia Clinic Directors of Canada.  Journal Articles
• Hemostatic Efficacy and Anti-FXa (Factor Xa) Reversal With Andexanet Alfa in Intracranial Hemorrhage: ANNEXA-4 Substudy  Journal Articles
• Heparan Sulfate Interacting Protein (HIP/L29) Negatively Regulates Growth Responses to Basic Fibroblast Growth Factor in Gingival Fibroblasts  Journal Articles
• Heparin and Low Molecular Weight Heparins Inhibit Prothrombinase Formation but not its Activity in Plasma  Journal Articles
• Heparin compromises streptokinase-induced arterial patency in rabbits  Journal Articles
• Heparin resistance in acute coronary syndromes  Journal Articles
• Heparin-Induced Thrombocytopenia  Journal Articles
• Heparin-Induced Thrombocytopenia: A Ten-Year Retrospective  Journal Articles
• Heparin-induced thrombocytopenia and cardiac surgery  Journal Articles
• Heparin-induced thrombocytopenia and cardiac surgery  Journal Articles
• Heparin-induced thrombocytopenia and its treatment.  Conferences
• Heparin-induced thrombocytopenia in intensive care patients  Journal Articles
• Heparin-induced thrombocytopenia in the critical care setting: Diagnosis and management^  Journal Articles
• Herpes Simplex Virus (HSV) Glycoproteins B and K Inhibit Cell Fusion Induced by HSV Syncytial Mutants  Journal Articles
• Hierarchical and Ontogenic Positions Serve to Define the Molecular Basis of Human Hematopoietic Stem Cell Behavior  Journal Articles
• High efficacy of combined therapy with pegylated interferon plus ribavirin in patients with hemophilia and chronic hepatitis C.  Journal Articles
• High-level expression and mutagenesis of recombinant human phosphatidylcholine transfer protein using a synthetic gene: evidence for a C-terminal membrane binding domain.  Journal Articles
• High-yield expression and purification of isotopically labeled norcoclaurine synthase, a Bet v 1-homologous enzyme, from Thalictrum flavum for NMR studies  Journal Articles
• Hirudin and thrombosis prophylaxis  Journal Articles
• Hirudin causes more bleeding than heparin in a rabbit ear bleeding model  Journal Articles
• Hirulog in the Treatment of Unstable Angina  Journal Articles
• Homolog of tocopherol C methyltransferases catalyzes N methylation in anticancer alkaloid biosynthesis  Journal Articles
• How I treat target-specific oral anticoagulant–associated bleeding  Journal Articles
• How can we reverse bleeding in patients on direct oral anticoagulants?  Journal Articles
• Human Kallikrein 4: Quantitative Study in Tissues and Evidence for Its Secretion into Biological Fluids  Journal Articles
• Human Lung Fibroblast-derived Granulocyte-Macrophage Colony Stimulating Factor (GM-CSF) Mediates Eosinophil Survival In Vitro  Journal Articles
• Human bronchial and parenchymal fibroblasts display differences in basal inflammatory phenotype and response to IL‐17A  Journal Articles
• Human kallikrein 4: enzymatic activity, inhibition, and degradation of extracellular matrix proteins  Conferences
• Human recombinant interleukin 1 stimulates collagenase and prostaglandin E2 production by human synovial cells.  Journal Articles
• Human recombinant interleukin 1β suppresses acetylcholine release from rat myenteric plexus  Journal Articles
• Human tissue-type plasminogen activator releases fibrinopeptides A and B from fibrinogen.  Journal Articles
• IFN-gamma potentiates the accumulation of diacylglycerol in murine macrophages.  Journal Articles
• IL-6 stimulates vitronectin gene expression in vivo.  Journal Articles
• Iatrogenic causes of an ICH  Journal Articles
• Identification and Biochemical Studies on Novel Non-Nucleoside Inhibitors of the Enzyme Adenosine Kinase  Journal Articles
• Identification and Characterization of Hemoangiogenic Progenitors During Cynomolgus Monkey Embryonic Stem Cell Differentiation  Journal Articles
• Identification and Partial Purification of DnaK Homologue from Extremely Halophilic Archaebacteria, Halobacterium cutirubrum  Journal Articles
• Identification and characterization of a novel herpes simplex virus glycoprotein, gK, involved in cell fusion  Journal Articles
• Identification of Direct p73 Target Genes Combining DNA Microarray and Chromatin Immunoprecipitation Analyses  Journal Articles
• Identification of an alpha-1 antitrypsin variant with enhanced specificity for factor XIa by phage display, bacterial expression, and combinatorial mutagenesis  Journal Articles
• Identification of the Catalytic Residues of AroA (Enolpyruvylshikimate 3-Phosphate Synthase) Using Partitioning Analysis  Journal Articles
• Identification of the Ice-Binding Surface on a Type III Antifreeze Protein with a “Flatness Function” Algorithm  Journal Articles
• Identification of the MMRN1 Binding Region within the C2 Domain of Human Factor V  Journal Articles
• Identification of the Mechanism Responsible for the Increased Fibrin Specificity of TNK-Tissue Plasminogen Activator Relative to Tissue Plasminogen Activator  Journal Articles
• Immuno-Isolation in Oncology - A Mini-Review  Journal Articles
• Immunoelectron Microscopy Provides Evidence That Tumor Necrosis Factor Receptor-Associated Protein 1 (TRAP-1) Is a Mitochondrial Protein Which also Localizes at Specific Extramitochondrial Sites  Journal Articles
• Impact of Asian Race on Response to Combination Therapy With Peginterferon Alfa-2a and Ribavirin in Chronic Hepatitis C  Journal Articles
• Impaired hydrogen sulfide synthesis and IL-10 signaling underlie hyperhomocysteinemia-associated exacerbation of colitis  Journal Articles
• Increased levels of CD34+ hemopoietic progenitor cells in atopic subjects.  Journal Articles
• Induction of Antibodies Protecting against Transmissible Gastroenteritis Coronavirus (TGEV) by Recombinant Adenovirus Expressing TGEV Spike Protein  Journal Articles
• Inhibition of Warfarin Activity by Ribavirin  Journal Articles
• Inhibition of antigen-induced secretion in the rat jejunum by interferon alpha/beta.  Journal Articles
• Inhibition of the amplification reactions of blood coagulation by site-specific inhibitors of α-thrombin  Journal Articles
• Inhibitor development in haemophilia according to concentrate  Journal Articles
• Inhibitor development in non-severe haemophilia across Europe  Journal Articles
• Inhibitory effect of human recombinant interferon gamma on synthesis of acute phase proteins in human hepatoma Hep G2 cells stimulated by leukocyte cytokines, TNF alpha and IFN-beta 2/BSF-2/IL-6.  Journal Articles
• Inscribing the Perimeter of the PagP Hydrocarbon Ruler by Site-Specific Chemical Alkylation  Journal Articles
• Insulin-like growth factor binding protein-2 modulates podocyte mitogenesis  Journal Articles
• Insulinlike Growth Factor I Plus Insulinlike Growth Factor Binding Protein 3 Attenuates the Proinflammatory Acute Phase Response in Severely Burned Children  Journal Articles
• Insulinlike Growth Factor I in Combination With Insulinlike Growth Factor Binding Protein 3 Affects the Hepatic Acute Phase Response and Hepatic Morphology in Thermally Injured Rats  Journal Articles
• Interaction of Human IgE with Fc Epsilon RI Alpha Exposes Hidden Epitopes on IgE  Journal Articles
• Interaction with a Membrane Surface Triggers a Reversible Conformational Change in Bax Normally Associated with Induction of Apoptosis  Journal Articles
• Interactions of Hemopoietic Cytokines on Differentiation of HL-60 Cells  Journal Articles
• Interferon beta 2/B-cell stimulatory factor type 2 shares identity with monocyte-derived hepatocyte-stimulating factor and regulates the major acute phase protein response in liver cells.  Journal Articles
• Interleukin 1β induces the expression of interleukin 6 in rat intestinal smooth muscle cells  Journal Articles
• Interleukin 1β-induced increase in substance P in rat myenteric plexus  Journal Articles
• Interleukin-1 beta modulation of norepinephrine release from rat myenteric nerves  Journal Articles
• Interleukin-5 is a human basophilopoietin: induction of histamine content and basophilic differentiation of HL-60 cells and of peripheral blood basophil-eosinophil progenitors  Journal Articles
• Interleukin-6 Increases Insulin-Stimulated Glucose Disposal in Humans and Glucose Uptake and Fatty Acid Oxidation In Vitro via AMP-Activated Protein Kinase  Journal Articles
• Interleukin-6 is a centrally acting endogenous pyrogen in the rat  Journal Articles
• Interleukin‐15 Contributes to the Regulation of Murine Adipose Tissue and Human Adipocytes  Journal Articles
• Interleukin‐4 and RANTES expression in maturing eosinophils derived from human cord blood CD34⁺ progenitors  Journal Articles
• Intra-arterial Prourokinase for Acute Ischemic Stroke  Journal Articles
• Intranasal Exposure of Mice to House Dust Mite Elicits Allergic Airway Inflammation via a GM-CSF-Mediated Mechanism  Journal Articles
• Intrapleural Dornase and Tissue Plasminogen Activator in pediatric empyema (DTPA): a study protocol for a randomized controlled trial  Journal Articles
• Investigating the role of the interleukin-23/-17A axis in rheumatoid arthritis  Journal Articles
• Iron-Dependent Hydrogenases ofEntamoeba histolyticaandGiardia lamblia:Activity of the Recombinant Entamoebic Enzyme and Evidence for Lateral Gene Transfer  Journal Articles
• Kidney growth and renal functions under the growth hormone replacement therapy in children  Journal Articles
• Kinetic Analysis of a Unique Direct Prothrombinase, fgl2, and Identification of a Serine Residue Critical for the Prothrombinase Activity  Journal Articles
• LETTERS TO THE EDITOR  Journal Articles
• Lanthionine−Somatostatin Analogs:  Synthesis, Characterization, Biological Activity, and Enzymatic Stability Studies  Journal Articles
• Lessons from a systematic literature review of the effectiveness of recombinant factor VIIa in acquired haemophilia  Journal Articles
• Lessons learned from the Sunbelt Melanoma Trial  Journal Articles
• Leukemia inhibitory factor increases glucose uptake in mouse skeletal muscle  Journal Articles
• Leukemia inhibitory factor mediates cytokine-induced suppression of myenteric neurotransmitter release from rat intestine  Journal Articles
• Leukotrienes in cerebrospinal fluid of the conscious cat: effect of platelet-activating factor and pyrogens.  Journal Articles
• Limitation of myocardial infarction by early infusion of recombinant tissue-type plasminogen activator.  Journal Articles
• Limited Fibrin Specificity of Tissue-type Plasminogen Activator and Its Potential Link to Bleeding  Journal Articles
• Limited effects of recombinant human and murine interleukin 1 and tumour necrosis factor on production of acute phase proteins by cultured rat hepatocytes.  Journal Articles
• Lipid binding protein response to a bile acid library: a combined NMR and statistical approach  Journal Articles
• Local Delivery of GM-CSF Protects Mice from Lethal Pneumococcal Pneumonia  Journal Articles
• Localization of full-length recombinant human proteoglycan-4 in commercial contact lenses using confocal microscopy  Conferences
• Localization of the Thrombin-binding Domain on Prothrombin Fragment 2  Journal Articles
• Location of the multimerin 1 binding site in coagulation factor V: An update  Journal Articles
• Long-Term Efficacy of Modified-Release Recombinant Human Thyrotropin Augmented Radioiodine Therapy for Benign Multinodular Goiter: Results from a Multicenter, International, Randomized, Placebo-Controlled, Dose-Selection Study  Journal Articles
• Low salt concentrations activate AMP-activated protein kinase in mouse macula densa cells  Journal Articles
• Maintenance treatment of renal anaemia in haemodialysis patients with methoxy polyethylene glycol-epoetin beta versus darbepoetin alfa administered monthly: a randomized comparative trial  Journal Articles
• Management of Excessive Anticoagulant Effect Due to Vitamin K Antagonists  Journal Articles
• Management of bleeding disorders: basic science  Journal Articles
• Management of heparin-induced thrombocytopenia: a critical comparison of lepirudin and argatroban  Journal Articles
• Mechanism of Action of Compound-13: An α1-Selective Small Molecule Activator of AMPK  Journal Articles
• Mechanism of allosteric inhibition in the Plasmodium falciparum cGMP-dependent protein kinase  Conferences
• Meta-Analysis Comparing Bivalirudin Versus Heparin Monotherapy on Ischemic and Bleeding Outcomes After Percutaneous Coronary Intervention  Journal Articles
• Meta-Analysis of Effects of Bivalirudin Versus Heparin on Myocardial Ischemic and Bleeding Outcomes After Percutaneous Coronary Intervention  Journal Articles
• Meta-analysis on recombinant versus urinary follicle stimulating hormone  Journal Articles
• Metabolic changes in rats during a continuous infusion of recombinant interleukin-1  Journal Articles
• Metabolic suppression identifies new antibacterial inhibitors under nutrient limitation  Journal Articles
• Methodologic pitfalls in assessing the efficacy of recombinant follicle-stimulating hormone versus human menopausal gonadotropin in assisted reproduction  Journal Articles
• Methodologies for data collection in congenital haemophilia with inhibitors (CHwI): critical assessment of the literature and lessons learned from recombinant factor VIIa  Journal Articles
• Microcapsules as Bio‐organs for Somatic Gene Therapy^a  Conferences
• Modeling the coupled extracellular and intracellular environments in mammalian cell culture  Journal Articles
• Models of cost-effectiveness of recombinant FSH versus urinary FSH  Journal Articles
• Modified-Release Recombinant Human TSH (MRrhTSH) Augments the Effect of¹³¹I Therapy in Benign Multinodular Goiter: Results from a Multicenter International, Randomized, Placebo-Controlled Study  Journal Articles
• Modulation of Clearance of Recombinant Serum Albumin by Either Glycosylation or Truncation  Journal Articles
• Modulation of adjuvant arthritis in Lewis rats by recombinant vaccinia virus expressing the human 60-kilodalton heat shock protein  Journal Articles
• Modulation of the Hypermetabolic Response to Trauma: Temperature, Nutrition, and Drugs  Journal Articles
• Molecular Cloning and Expression of Rabbit Heparin Cofactor II: A Plasma Thrombin Inhibitor Highly Conserved between Species  Journal Articles
• Molecular cloning and functional expression of rabbit α2-antiplasmin  Journal Articles
• Molecular mechanism of VanHst, an alpha-ketoacid dehydrogenase required for glycopeptide antibiotic resistance from a glycopeptide producing organism  Journal Articles
• Molecules in focus Transforming growth factor-beta (TGF-β)  Journal Articles
• Monoclonal antibodies raised against Xenopus p53 interact with human p73  Journal Articles
• Monocyte-Macrophage Differentiation Induced by Human Upper Airway Epithelial Cells  Journal Articles
• Mucosal Immunity and Protection after Intranasal Immunization with Recombinant Adenovirus Expressing Herpes Simplex Virus Glycoprotein B  Journal Articles
• Multicentric Evaluation of a New PT Reagent Based on Recombinant Human Tissue Factor and Synthetic Phospholipids  Journal Articles
• Multicentric evaluation of heparinase on aPTT, thrombin clotting time and a new PT reagent based on recombinant human tissue factor  Journal Articles
• Multimerin 1 binds factor V and activated factor V with high affinity and inhibits thrombin generation  Journal Articles
• Murine Cardiotrophin-1 Stimulates the Acute-Phase Response in Rat Hepatocytes and H35 Hepatoma Cells  Journal Articles
• Murine Oncostatin M Stimulates Mouse Synovial Fibroblasts in Vitro and Induces Inflammation and Destruction in Mouse Joints in Vivo  Journal Articles
• Musculoskeletal health of subjects with hemophilia A treated with tailored prophylaxis: Canadian Hemophilia Primary Prophylaxis (CHPS) Study  Journal Articles
• Mutation of Any Site of N-Linked Glycosylation Accelerates the In Vivo Clearance of Recombinant Rabbit Antithrombin  Journal Articles
• Mutual Protein-Ligand Conformational Selection Drives cGMP vs. cAMP Selectivity in Protein Kinase G  Journal Articles
• Myostatin promotes a fibrotic phenotypic switch in multipotent C3H 10T1/2 cells without affecting their differentiation into myofibroblasts  Journal Articles
• NMR assignment of the cAMP-binding domain A of the PKA regulatory subunit  Journal Articles
• NOAC monitoring, reversal agents, and post-approval safety and effectiveness evaluation: A cardiac safety research consortium think tank  Journal Articles
• Natural And Recombinant ANTI-IgE Autoantibodies  Journal Articles
• Network meta-analysis of direct-acting antivirals in combination with peginterferon–ribavirin for previously untreated patients with hepatitis C genotype 1 infection  Journal Articles
• Neutral endopeptidase (EC 3.4.24.11) terminates colitis by degrading substance P  Journal Articles
• Neutralization of Heparin Activity  Journal Articles
• New Anti-thrombotic Agents: Emphasis on Hemorrhagic Complications and Their Management  Conferences
• No Evidence for Direct Activation of the Cystic Fibrosis Transmembrane Conductance Regulator by 8-Cyclopentyl-1,3-Dipropylxanthine  Journal Articles
• Nonautologous gene therapy with implantable devices  Journal Articles
• Noncanonical protein kinase A activation by oligomerization of regulatory subunits as revealed by inherited Carney complex mutations  Journal Articles
• Normally suppressing CD40 coregulatory signals delivered by airway macrophages to TH2 lymphocytes are defective in patients with atopic asthma  Journal Articles
• Novel method for differentiation between Trastuzumab and host adaptive response  Journal Articles
• Novel oral anticoagulants and reversal agents: Considerations for clinical development  Journal Articles
• Novel therapy for asthma  Journal Articles
• Nucleic Acid Sequence Based Amplification (NASBA) of Chlamydia pneumoniae Major Outer Membrane Protein (ompA) mRNA with Bioluminescent Detection  Journal Articles
• O2 sensing by recombinant TWIK-related halothane-inhibitable K+ channel-1 background K+ channels heterologously expressed in human embryonic kidney cells  Journal Articles
• Observations on intramammary infection and somatic cell counts in cows treated with recombinant bovine somatotropin.  Journal Articles
• Off-label use of recombinant activated factor VII in surgical and non-surgical patients at 16 Canadian hospitals from 2007 to 2010 (Canadian Registry Report)  Journal Articles
• On-Label Versus Off-Label Use of Recombinant Activated Factor VII: A Comprehensive Review of Use in Two Canadian Centers  Journal Articles
• Oncogenes belonging to the CSF-1 transduction pathway direct p53 tumor suppressor effects to monocytic differentiation in 32D cells  Journal Articles
• One-pot chemoenzymatic preparation of coenzyme A analogues  Journal Articles
• Optimal reversal of vitamin K antagonists  Journal Articles
• Optimising parameters for peripheral blood leukapheresis after r-metHuG-CSF (filgrastim) and r-metHuSCF (ancestim) in patients with multiple myeloma: a temporal analysis of CD34+ absolute counts and subsets  Journal Articles
• Orthopaedic surgery in haemophilia patients with inhibitors: a practical guide to haemostatic, surgical and rehabilitative care  Journal Articles
• Otamixaban in acute coronary syndromes  Journal Articles
• Outcomes of Chronic Hepatitis C Therapy in Patients Treated in Community Versus Academic Centres in Canada: Final Results of APPROACH (A Prospective Study of Peginterferon alfa-2a and Ribavirin at Academic and Community Centres in Canada)  Journal Articles
• Overexpression of Tumor Necrosis Factor-α Diminishes Pulmonary Fibrosis Induced by Bleomycin or Transforming Growth Factor-β  Journal Articles
• Overexpression of human prostaglandin G/H synthase-1 and -2 by recombinant vaccinia virus: inhibition by nonsteroidal anti-inflammatory drugs and biosynthesis of 15-hydroxyeicosatetraenoic acid.  Journal Articles
• Overexpression, Purification, and Crystallization of the DNA Binding and Dimerization Domains of the Epstein-Barr Virus Nuclear Antigen 1  Journal Articles
• Oviductal Antibody Response to a Defined Recombinant Sperm Antigen in Macaques1  Journal Articles
• Ovulation induction in women with polycystic ovary syndrome: randomized trial of clomiphene citrate versus low-dose recombinant FSH as first line therapy  Journal Articles
• Oxidative stress contributes to the induction and persistence of TGF-β1 induced pulmonary fibrosis  Journal Articles
• PKC-β1 Mediates Glucose-Induced Akt Activation and TGF-β1 Upregulation in Mesangial Cells  Journal Articles
• Parenteral Anticoagulants  Journal Articles
• Parenteral Anticoagulants  Journal Articles
• Patient data meta‐analysis of Post‐Authorization Safety Surveillance (PASS) studies of haemophilia A patients treated with rAHF‐PFM  Journal Articles
• Peginterferon Plus Ribavirin for Chronic Hepatitis C in Patients With Human Immunodeficiency Virus  Journal Articles
• Peginterferon alpha-2a is associated with higher sustained virological response than peginterferon alfa-2b in chronic hepatitis C: Systematic review of randomized trials  Journal Articles
• Peginterferon alpha-2a versus peginterferon alpha-2b for chronic hepatitis C  Journal Articles
• Peginterferon plus ribavirin versus interferon plus ribavirin for chronic hepatitis C  Journal Articles
• Peptide and Recombinant Immunotherapy  Journal Articles
• Peritoneal morphological and functional changes associated with platelet-derived growth factor B  Journal Articles
• Pharmacokinetics of plasma‐derived vs. recombinant FVIII concentrates: a comparative study  Journal Articles
• Pharmacologic tools to reduce bleeding in surgery.  Journal Articles
• Pharmacomechanical Catheter-Directed Thrombolysis for Deep-Vein Thrombosis  Journal Articles
• Phase I Clinical Trial of Recombinant Human Interleukin-3 Combined With Carboplatin in the Treatment of Patients With Recurrent Ovarian Carcinoma  Journal Articles
• Phase III trial to evaluate the efficacy of maintaining hemoglobin levels above 12.0 g/dL with erythropoietin vs above 10.0 g/dL without erythropoietin in anemic patients receiving concurrent radiation and cisplatin for cervical cancer  Journal Articles
• PilN Binding Modulates the Structure and Binding Partners of the Pseudomonas aeruginosa Type IVa Pilus Protein PilM  Journal Articles
• Platelet Adhesion and Fibrinogen Accretion on a Family of Elastin-Like Polypeptides  Journal Articles
• Population‐based modeling of the progression of apoptosis in mammalian cell culture  Journal Articles
• Porcine Collagenase from Synovial Fibroblasts: cDNA Sequence and Modulation of Expression of RNA In Vitro by Various Cytokines  Journal Articles
• Potential dangers in the customary methods of conducting meta-analyses: Lack of bias in the meta-analysis of recombinant versus urinary follicle stimulating hormone  Journal Articles
• Practical management of bleeding in patients receiving non-vitamin K antagonist oral anticoagulants  Journal Articles
• Preparation and X-ray crystallographic analysis of recombinant obelin crystals diffracting to beyond 1.1 Å  Journal Articles
• Preparation and preliminary study of crystals of the recombinant calcium-regulated photoprotein obelin from the bioluminescent hydroid Obelia longissima  Journal Articles
• Pretreatment of Rabbits With Either Hirudin, Ancrod, or Warfarin Significantly Reduces the Immediate Uptake of Fibrinogen and Platelets by the Deendothelialized Aorta Wall After Balloon-Catheter Injury In Vivo  Journal Articles
• ProNGF: a neurotrophic or an apoptotic molecule?  Journal Articles
• Probability of thrombosis of vascular access among hemodialysis patients treated with recombinant human erythropoietin.  Journal Articles
• Protective Immunity to Rotavirus-Induced Diarrhoea Is Passively Transferred to Newborn Mice from Naive Dams Vaccinated with a Single Dose of a Recombinant Adenovirus Expressing Rotavirus VP7sc  Journal Articles
• Protein kinase A-catalyzed phosphorylation of heat shock protein 60 chaperone regulates its attachment to histone 2B in the T lymphocyte plasma membrane  Journal Articles
• Proteins of the Glycine Decarboxylase Complex in the Hydrogenosome ofTrichomonas vaginalis  Journal Articles
• Protocolized Anemia Management with Erythropoietin in Hemodialysis Patients  Journal Articles
• Pseudomonas aeruginosa Minor Pilins Prime Type IVa Pilus Assembly and Promote Surface Display of the PilY1 Adhesin  Journal Articles
• Psychological Aspects of the Canadian Randomized Controlled Trial of Human Growth Hormone and Low-Dose Ethinyl Oestradiol in Children with Turner Syndrome  Journal Articles
• Purification and characterization of human interleukin‐1β expressed in recombinant Escherichia coli  Journal Articles
• Purification and characterization of soluble forms of human and rat stem cell factor recombinantly expressed by Escherichia coli and by Chinese hamster ovary cells  Journal Articles
• Purification and characterization of the carboxyl-terminal transactivation domain of Vmw65 from herpes simplex virus type 1.  Journal Articles
• Purification of Recombinant Human Hsp60: Use of a GroEL-free Preparation to Assess Autoimmunity in Rheumatoid Arthritis  Journal Articles
• Purification, crystallization and X-ray diffraction analysis of pavineN-methyltransferase fromThalictrum flavum  Journal Articles
• Purified, Recombinant TagF Protein from Bacillus subtilis 168 Catalyzes the Polymerization of Glycerol Phosphate onto a Membrane Acceptor in Vitro  Journal Articles
• Quorum sensing in Escherichia coli , Salmonella typhimurium , and Vibrio harveyi : A new family of genes responsible for autoinducer production  Journal Articles
• Radiolabeled r-Hirudin as a Measure of Thrombin Activity at, or within, the Rabbit Aorta Wall In Vitro and In Vivo  Journal Articles
• Randomized Controlled Trial to Determine the Efficacy of Long-Term Growth Hormone Treatment in Severely Burned Children  Journal Articles
• Randomized trial of interferon maintenance in multiple myeloma: a study of the National Cancer Institute of Canada Clinical Trials Group.  Journal Articles
• Randomized, Double-Blind, Placebo-Controlled Trial of Epoetin Alfa in Men With Castration-Resistant Prostate Cancer and Anemia  Journal Articles
• Randomized, Double-Blind, Placebo-Controlled Trial of Erythropoietin in Non–Small-Cell Lung Cancer With Disease-Related Anemia  Journal Articles
• Reactivation of coagulation after stopping infusions of recombinant hirudin and unfractionated heparin in unstable angina and myocardial infarction without ST elevation: results of a randomized trial  Journal Articles
• Reactivation of ischemic events in acute coronary syndromes: results from GUSTO-IIb  Journal Articles
• Reactivation of ischemic events in acute coronary syndromes: results from GUSTO-IIb. Gobal Use of Strategies To Open occluded arteries in acute coronary syndromes.  Journal Articles
• Real-world effectiveness of peginterferon α-2b plus ribavirin in a Canadian cohort of treatment-naïve chronic hepatitis C patients with genotypes 2 or 3: results of the PoWer and RediPEN studies  Journal Articles
• Recent Advances in Antidotes for Direct Oral Anticoagulants: Their Arrival Is Imminent  Journal Articles
• Recombinant FVIIa in children with liver disease  Journal Articles
• Recombinant Factor VIIa in Multiple Surgery  Journal Articles
• Recombinant Human Erythropoietin: Factors to Consider in Cost-Benefit Analysis  Journal Articles
• Recombinant Human Growth Hormone Alters Acute Phase Reactant Proteins, Cytokine Expression, and Liver Morphology in Burned Rats  Journal Articles
• Recombinant Truncated Dystrophin Minigenes: Construction, Expression, and Adenoviral Delivery  Journal Articles
• Recombinant activated factor VII for the treatment of life-threatening haemorrhage  Journal Articles
• Recombinant albumins containing additional peptide sequences smaller than barbourin retain the ability of barbourin-albumin to inhibit platelet aggregation  Journal Articles
• Recombinant factor VIII concentrate  Journal Articles
• Recombinant factor VIIa (rFVIIa) and hemodialysis to manage massive dabigatran-associated postcardiac surgery bleeding  Journal Articles
• Recombinant factor VIIa concentrate versus plasma-derived concentrates for treating acute bleeding episodes in people with haemophilia and inhibitors  Journal Articles
• Recombinant oncostatin M stimulates the production of acute phase proteins in HepG2 cells and rat primary hepatocytes in vitro.  Journal Articles
• Recombinant versus urinary follicle stimulating hormone for ovarian stimulation in assisted reproduction  Journal Articles
• Recombinant versus urinary follicle stimulating hormone for ovarian stimulation in assisted reproduction cycles  Journal Articles
• Recombinant versus urinary follicle stimulating hormone for ovarian stimulation in assisted reproduction cycles  Journal Articles
• Recovery of functionally‐active protein from inclusion bodies using a thermal‐cycling method  Journal Articles
• Reduced Dose Bolus Alteplase vs Conventional Alteplase Infusion for Pulmonary Embolism Thrombolysis  Journal Articles
• Reduction Precedes Cytidylyl Transfer without Substrate Channeling in Distinct Active Sites of the Bifunctional CDP-Ribitol Synthase from Haemophilus influenzae  Journal Articles
• Reduction of Nilutamide by NO Synthases:  Implications for the Adverse Effects of This Nitroaromatic Antiandrogen Drug  Journal Articles
• Regulation of IL-6 and the hepatic IL-6 receptor in acute inflammation in vivo  Journal Articles
• Regulation of NADH/CoQ Oxidoreductase: Do Phosphorylation Events Affect Activity?  Journal Articles
• Regulation of Smurf2 Ubiquitin Ligase Activity by Anchoring the E2 to the HECT Domain  Journal Articles
• Reinduction of remission of chronic myeloid leukemia by donor leukocyte transfusion following relapse after bone marrow transplantation: recovery complicated by initial pancytopenia and late dermatomyositis.  Journal Articles
• Replacement therapy with recombinant factor IX. A multicentre evaluation of current dosing practices in Italy.  Journal Articles
• Requirement of Lysine Residues Outside of the Proposed Pentasaccharide Binding Region for High Affinity Heparin Binding and Activation of Human Antithrombin III  Journal Articles
• Rescue, propagation, and partial purification of a helper virus-dependent adenovirus vector.  Journal Articles
• Restart of Anticoagulant Therapy and Risk of Thrombosis, Rebleeding, and Death after Factor Xa Inhibitor Reversal in Major Bleeding Patients  Journal Articles
• Results of a Prospective Randomized Trial Evaluating Surgery Versus Thrombolysis for Ischemia of the Lower Extremity The STILE Trial  Journal Articles
• Results of the Canadian morbidity study in end-stage renal disease patients treated by hemodialysis.  Journal Articles
• Retention of thrombin inhibitory activity by recombinant serpins expressed as integral membrane proteins tethered to the surface of mammalian cells  Journal Articles
• Retreatment with Pegylated Interferon Alpha-2a and Ribavirin in Patients with Chronic Hepatitis C Who Have Relapsed or Not Responded to a First Course of Pegylated Interferon-Based Therapy  Journal Articles
• Reversal agents for current and forthcoming direct oral anticoagulants  Journal Articles
• Reversal agents for non-vitamin K antagonist oral anticoagulants  Journal Articles
• Reversal of Direct Oral Anticoagulants: Current Status and Future Directions  Journal Articles
• Reversal of New, Factor-specific Oral Anticoagulants by rFVIIa, Prothrombin Complex Concentrate and Activated Prothrombin Complex Concentrate: A Review of Animal and Human Studies  Journal Articles
• Reversal of direct oral anticoagulants: Guidance from the Anticoagulation Forum  Journal Articles
• Reversal of direct oral anticoagulants: a practical approach  Journal Articles
• Reversal of direct oral anticoagulants: guidance from the SSC of the ISTH  Journal Articles
• Review of pumps for continuous infusion of coagulation factor concentrates: what are the options?  Conferences
• Rifampin phosphotransferase is an unusual antibiotic resistance kinase  Journal Articles
• Risk of Stent Thrombosis and Major Bleeding with Bivalirudin Compared with Active Control: A Systematic Review and Meta-analysis of Randomized Trials  Journal Articles
• Role of Eotaxin-1 (CCL11) and CC Chemokine Receptor 3 (CCR3) in Bleomycin-Induced Lung Injury and Fibrosis  Journal Articles
• Role of IL-12 in macrophage activation during intracellular infection: IL-12 and mycobacteria synergistically release TNF-α and nitric oxide from macrophages via IFN-γ induction  Journal Articles
• S100A6 is a negative regulator of the induction of cardiac genes by trophic stimuli in cultured rat myocytes  Journal Articles
• SUCCESSFUL USE OF RECOMBINANT FACTOR VIIa IN PATIENT WITH SEVERE HAEMOPHILIA A DURING SYNOVECTOMY  Journal Articles
• Safety and efficacy of sucrose-formulated full-length recombinant factor VIII: Experience in the standard clinical setting  Journal Articles
• Safety and physiological effects of two different doses of elosulfase alfa in patients with morquio a syndrome: A randomized, double‐blind, pilot study  Journal Articles
• Safety, efficacy and lessons from continuous infusion with rFVIIa  Conferences
• Safety, efficacy and lessons from continuous infusion with rFVIIa. rFVIIa-CI Group.  Journal Articles
• Scavenger receptor Bl - a cell surface receptor for high density lipoprotein  Journal Articles
• Screening recombinant baculovirus plaques in situ with antibody probes  Journal Articles
• Seizures, headache and thrombocytopenia: diagnosis and treatment do not always come in a standard sequence  Journal Articles
• Selective binding of C-6 OH sulfated hyaluronic acid to the angiogenic isoform of VEGF165  Journal Articles
• Self-Assembly Enhances the Strength of Fibers Made from Vimentin Intermediate Filament Proteins  Journal Articles
• Serine-401 as a batrachotoxin- and local anesthetic-sensing residue in the human cardiac Na+ channel  Journal Articles
• Severe acute respiratory syndrome coronavirus nucleocapsid protein expressed by an adenovirus vector is phosphorylated and immunogenic in mice  Journal Articles
• Simoctocog Alfa (Nuwiq) in Previously Untreated Patients with Severe Haemophilia A: Final Results of the NuProtect Study  Journal Articles
• Simultaneous Phase Transition of ELP Tagged Molecules and Free ELP:  An Efficient and Reversible Capture System  Journal Articles
• Site‐directed mutagenesis of the P2 residue of human antithrombin  Journal Articles
• Skin-type Antifreeze Protein from the Shorthorn Sculpin,Myoxocephalus scorpius  Journal Articles
• Soluble fibrin degradation products potentiate tissue plasminogen activator-induced fibrinogen proteolysis.  Journal Articles
• Somatic Gene Therapy for a Neurodegenerative Disease Using Microencapsulated Recombinant Cells  Journal Articles
• Spatial structure of the novel light-sensitive photoprotein berovin from the ctenophore Beroe abyssicola in the Ca2+-loaded apoprotein conformation state  Journal Articles
• Specific immunotherapy  Journal Articles
• Spectinomycin kinase from Legionella pneumophila. Characterization of substrate specificity and identification of catalytically important residues  Journal Articles
• Stability and sterility of recombinant tissue plasminogen activator at −30°C  Journal Articles
• Staining of endothelial cells and macrophages in atherosclerotic lesions with human heat-shock protein-reactive antisera.  Journal Articles
• Streptokinase and rt-PA activate platelets by a different way: implications on the rethrombosis rate after their administration in myocardial infarction.  Journal Articles
• Structural Basis for Cyclic-Nucleotide Selectivity and cGMP-Selective Activation of PKG I  Journal Articles
• Structural Characterization of Novel Pseudomonas aeruginosa Type IV Pilins  Journal Articles
• Structural Characterization of a Novel Chlamydia pneumoniae Type III Secretion-Associated Protein, Cpn0803  Journal Articles
• Structure and Function of Sedoheptulose-7-phosphate Isomerase, a Critical Enzyme for Lipopolysaccharide Biosynthesis and a Target for Antibiotic Adjuvants  Journal Articles
• Structure and Functional Relationships in Human pur H  Journal Articles
• Structure-Function Analyses of Thrombomodulin by Gene-Targeting in Mice: The Cytoplasmic Domain Is Not Required for Normal Fetal Development  Journal Articles
• Structure-guided optimization of protein kinase inhibitors reverses aminoglycoside antibiotic resistance  Journal Articles
• Structure–function studies on Hsp47: pH-dependent inhibition of collagen fibril formation in vitro  Journal Articles
• Substance P increases in vitro lymphokine-activated-killer (LAK) cell cytotoxicity against fresh colorectal cancer cells  Journal Articles
• Subtype- and response element-dependent differences in transactivation by peroxisome proliferator-activated receptors α and γ  Journal Articles
• Successful treatment with rFVIIa of spontaneous intracerebral hemorrhage in a patient with mechanical prosthetic heart valves  Journal Articles
• Sudden Enlargement of Local Recurrent Thyroid Tumor after Recombinant Human TSH Administration  Journal Articles
• Sudden Enlargement of Local Recurrent Thyroid Tumor after Recombinant Human TSH Administration  Journal Articles
• Suicide risk in hepatitis C and during interferon-alpha therapy: a review and clinical update  Journal Articles
• Surface-Functionalized Model Contact Lenses with a Bioinspired Proteoglycan 4 (PRG4)-Grafted Layer  Journal Articles
• Surveillance for Factor VIII Inhibitor Development in the Canadian Hemophilia A Population Following the Widespread Introduction of Recombinant Factor VIII Replacement Therapy  Journal Articles
• Surviving Sepsis Campaign: International guidelines for management of severe sepsis and septic shock: 2008  Journal Articles
• Sustained antithrombotic activity of hirudin after its plasma clearance: comparison with heparin  Journal Articles
• Switching patients in the age of long-acting recombinant products?  Journal Articles
• Symbiotic nitrogen fixation by a nifA deletion mutant of Rhizobium meliloti: the role of an unusual ntrC allele  Journal Articles
• Synergism between interleukins 1β and 6 on noradrenergic nerves in rat myenteric plexus  Journal Articles
• Synergistic effects of nerve growth factor and granulocyte-macrophage colony-stimulating factor on human basophilic cell differentiation  Journal Articles
• Synoviocyte derived granulocyte macrophage colony stimulating factor mediates the survival of human lymphocytes.  Journal Articles
• Synthesis and Processing of the Haemagglutinin--esterase Glycoprotein of Bovine Coronavirus Encoded in the E3 Region of Adenovirus  Journal Articles
• Synthesis and Structure–Activity Relationships of the First Ferrocenyl-Aryl-Hydantoin Derivatives of the Nonsteroidal Antiandrogen Nilutamide  Journal Articles
• Synthesis and in Vitro Evaluation of¹⁸F- and¹⁹F-Labeled Insulin:  A New Radiotracer for PET-based Molecular Imaging Studies  Journal Articles
• Systemic administration of ciliary neurotrophic factor induces cachexia in rodents.  Journal Articles
• TNF‐α  mediates the induction of nitric oxide synthase in macrophages but not in neutrophils in experimental cutaneous leishmaniasis  Journal Articles
• Targeting Anemia with Erythropoietin during Critical Illness  Journal Articles
• Temporal changes in MMP mRNA expression in the lens epithelium during anterior subcapsular cataract formation  Journal Articles
• TetX Is a Flavin-dependent Monooxygenase Conferring Resistance to Tetracycline Antibiotics  Journal Articles
• The Arginine-Rich Domains Present in Human Immunodeficiency Virus Type 1 Tat and Rev Function as Direct Importin β-Dependent Nuclear Localization Signals  Journal Articles
• The COOH terminus of aminoglycoside phosphotransferase (3')-IIIa is critical for antibiotic recognition and resistance  Journal Articles
• The Effect of Antithrombin III-Independent Thrombin Inhibitors and Heparin on Fibrin Accretion onto Fibrin-Coated Polyethylene \textbar Request PDF  Journal Articles
• The Effect of Growth Hormone on Gut Mucosal Homeostasis and Cellular Mediators after Severe Trauma  Journal Articles
• The Effect of Inorganic Phosphate on the Activity of Bacterial Ribokinase  Journal Articles
• The Effects of Leptin on Airway Smooth Muscle Responses  Journal Articles
• The Efficacy and Safety of Andexanet Alfa in Patients With Acute Gastrointestinal Bleeding While Taking Factor Xa Inhibitors: An ANNEXA-4 Subanalysis  Journal Articles
• The Herpes Simplex Virus 1-Encoded Envelope Glycoprotein B Activates NF-κB through the Toll-Like Receptor 2 and MyD88/TRAF6-Dependent Signaling Pathway  Journal Articles
• The Heterodimeric Glycoprotein Hormone, GPA2/GPB5, Regulates Ion Transport across the Hindgut of the Adult Mosquito, Aedes aegypti  Journal Articles
• The Himar1 mariner transposase cloned in a recombinant adenovirus vector is functional in mammalian cells  Journal Articles
• The Ice-Binding Site of Atlantic Herring Antifreeze Protein Corresponds to the Carbohydrate-Binding Site of C-Type Lectins  Journal Articles
• The Myxoma Virus-soluble Interferon- γ Receptor Homolog, M-T7, Inhibits Interferon- γ in a Species-specific Manner  Journal Articles
• The Non-Vitamin K Antagonist Oral Anticoagulants in Heart Disease: Section V—Special Situations  Journal Articles
• The PARADIGHM (physicians advancing disease knowledge in hypoparathyroidism) registry for patients with chronic hypoparathyroidism: study protocol and interim baseline patient characteristics  Journal Articles
• The Real Decoy  Journal Articles
• The Rodin (Research Of Determinants of INhibitor Development among PUPs with haemophilia) study: the clinical conundrum from the perspective of haemophilia treaters  Journal Articles
• The Role of Aluminum in the Functional Iron Deficiency of Patients Treated With Erythropoietin: Case Report of Clinical Characteristics and Response to Treatment  Journal Articles
• The Structural Integrity of Anion Binding Exosite I of Thrombin Is Required and Sufficient for Timely Cleavage and Activation of Factor V and Factor VIII  Journal Articles
• The TagB Protein in Bacillus subtilis 168 Is an Intracellular Peripheral Membrane Protein That Can Incorporate Glycerol Phosphate onto a Membrane-bound Acceptor in Vitro  Journal Articles
• The Tyrosine Kinase Substrate p120^cas Binds Directly to E-Cadherin but Not to the Adenomatous Polyposis Coli Protein or α-Catenin  Journal Articles
• The accumulation of 111In-eosinophils induced by inflammatory mediators, in vivo.  Journal Articles
• The benefits and harms of intravenous thrombolysis with recombinant tissue plasminogen activator within 6 h of acute ischaemic stroke (the third international stroke trial [IST-3]): a randomised controlled trial  Journal Articles
• The chimeric TAC receptor co-opts the T cell receptor yielding robust anti-tumor activity without toxicity  Journal Articles
• The current state of adverse event reporting in hemophilia  Journal Articles
• The cystic fibrosis transmembrane conductance regulator attenuates the endogenous Ca 2+ activated Cl - conductance of Xenopus oocytes  Journal Articles
• The direct binding of human factor VII in plasma to recombinant human tissue factor  Journal Articles
• The dynamic microbe: green fluorescent protein brings bacteria to light  Journal Articles
• The evolving role of direct thrombin inhibitors in acute coronary syndromes  Journal Articles
• The evolving role of direct thrombin inhibitors in acute coronary syndromes.  Journal Articles
• The functions of the A1A2A3 domains in von Willebrand factor include multimerin 1 binding  Journal Articles
• The impact of recombinant human erythropoietin on medical care costs for hemodialysis patients in Canada  Journal Articles
• The in vivo delivery of heterologous proteins by microencapsulated recombinant cells  Journal Articles
• The magnitude of the CD8+ T cell response produced by recombinant virus vectors is a function of both the antigen and the vector  Journal Articles
• The molecular basis of the expansive substrate specificity of the antibiotic resistance enzyme aminoglycoside acetyltransferase-6'-aminoglycoside phosphotransferase-2". The role of ASP-99 as an active site base important for acetyl transfer  Journal Articles
• The onerous task of comparing treatments in inhibitor patients  Journal Articles
• The organization to assess strategies for ischemic syndromes (OASIS) pilot study: evaluation of acute and long-term therapies for patients with acute coronary syndromes without ST elevation  Journal Articles
• The purified myxoma virus gamma interferon receptor homolog M-T7 interacts with the heparin-binding domains of chemokines  Journal Articles
• The relative kinetics of clotting and lysis provide a biochemical rationale for the correlation between elevated fibrinogen and cardiovascular disease  Journal Articles
• The role of recombinant factor VIIa in on-pump cardiac surgery: Proceedings of the Canadian Consensus Conference  Journal Articles
• The status of new anticoagulants  Journal Articles
• The structure of the apo cAMP‐binding domain of HCN4 – a stepping stone toward understanding the cAMP‐dependent modulation of the hyperpolarization‐activated cyclic‐nucleotide‐gated ion channels  Journal Articles
• The thrombolytic and hemorrhagic effects of tissue type plasminogen activator: Influence of dosage regimens in rabrits  Journal Articles
• The use of erythropoiesis-stimulating agents in patients with non-myeloid hematological malignancies: a systematic review  Journal Articles
• Therapeutic Peptides: New Arsenal Against Drug Resistant Pathogens  Journal Articles
• Thienopyridone Drugs Are Selective Activators of AMP-Activated Protein Kinase β1-Containing Complexes  Journal Articles
• Thrombin generation in vitro in the presence of by‐passing agents in siblings with severe haemophilia A  Journal Articles
• Thrombolysis Despite Recent Stroke  Journal Articles
• Thrombolysis by chemically modified coagulation factor Xa  Journal Articles
• Thrombolytic therapy for pulmonary embolism: is it effective? Is it safe? When is it indicated?  Journal Articles
• Thrombosis of the Cerebral Veins and Sinuses  Journal Articles
• Tissue plasminogen activator: Toronto (TPAT) placebo-controlled randomized trial in acute myocardial infarction  Journal Articles
• Total intracranial hemorrhage volume measurement summating all compartments best in traumatic and nontraumatic intracranial bleeding  Journal Articles
• Transforming Growth Factor-β: Activation by Neuraminidase and Role in Highly Pathogenic H5N1 Influenza Pathogenesis  Journal Articles
• Transient Global Amnesia as the Presenting Feature of Heparin-Induced Thrombocytopenia  Journal Articles
• Translational Success Stories  Journal Articles
• Transplanted hepatocytes infected with a complement receptor type 1 (CR1)-containing recombinant adenovirus are resistant to hyperacute rejection  Journal Articles
• Treatment and prevention of acute bleedings in von Willebrand disease – efficacy and safety of Wilate^®, a new generation von Willebrand factor/factor VIII concentrate  Journal Articles
• Treatment of Heparin-Induced Thrombocytopenia  Journal Articles
• Treatment of Prion Disease with Heterologous Prion Proteins  Journal Articles
• Treatment of the Chronic Phase of Chronic Myeloid Leukemia with an Intermittent Schedule of Recombinant Interferon Alfa-2b and Cytarabine: Results from CALGB Study 9013  Conferences
• Tumor necrosis factor enhances interferon-induced Ia antigen expression on murine islet parenchymal cells.  Journal Articles
• Tumour therapy in mice using adenovirus vectors expressing human TNFa.  Journal Articles
• Two Conserved Histidine Residues Are Critical to the Function of the TagF-like Family of Enzymes  Journal Articles
• Two Phase I Studies of Carboplatin Dose Escalation in Chemotherapy-Naive Ovarian Cancer Patients Supported With Patients Supported With Granulocyte-Macrophage Colony-Stimulating Factor  Journal Articles
• Two-Photon Activation and Excitation Properties of PA-GFP in the 720–920-nm Region  Journal Articles
• Type and intensity of FVIII exposure on inhibitor development in PUPs with haemophilia A  Journal Articles
• UDP-N-acetylmuramic Acid (UDP-MurNAc) Is a Potent Inhibitor of MurA (Enolpyruvyl-UDP-GlcNAc Synthase)  Journal Articles
• Understanding FVIII/VWF complex – report from a symposium of XXIX WFH meeting 2010  Journal Articles
• Unraveling Severe Sepsis  Journal Articles
• Updated meta-analysis of recombinant follicle-stimulating hormone (FSH) versus urinary FSH for ovarian stimulation in assisted reproduction  Journal Articles
• Use of Hirulog in the prevention of venous thrombosis after major hip or knee surgery.  Journal Articles
• Use of erythropoietins in patients with renal transplants  Journal Articles
• Utilization of recombinant activated factor VII in southern Ontario in 85 patients with and without haemophilia  Journal Articles
• Vascular Endothelial Growth Factor and Its Receptor, Flk-1/KDR, Are Cytoprotective in the Extravascular Compartment of the Ovarian Follicle  Journal Articles
• Venous limb gangrene during overlapping therapy with warfarin and a direct thrombin inhibitor for immune heparin‐induced thrombocytopenia  Journal Articles
• Vgb from Staphylococcus aureus inactivates streptogramin B antibiotics by an elimination mechanism not hydrolysis  Journal Articles
• Vimentin Exposed on Activated Platelets and Platelet Microparticles Localizes Vitronectin and Plasminogen Activator Inhibitor Complexes on Their Surface  Journal Articles
• Water-soluble formulation of Coenzyme Q10 inhibits Bax-induced destabilization of mitochondria in mammalian cells  Journal Articles
• We Need Both Evidence and Values to Navigate Uncertainty  Journal Articles
• What Is the Evidence for the Off-label Use of Recombinant Factor VIIa (rFVIIa) in the Acute Reversal of Warfarin?  Journal Articles
• When and how to use antidotes for the reversal of direct oral anticoagulants: guidance from the SSC of the ISTH  Journal Articles
• Which antithrombotic to use during PCI?  Journal Articles
• Wild-Type p53 Induces Diverse Effects in 32D Cells Expressing Different Oncogenes  Journal Articles
• XPF with mutations in its conserved nuclease domain is defective in DNA repair but functions in TRF2-mediated telomere shortening  Journal Articles
• YjeQ, an Essential, Conserved, Uncharacterized Protein from Escherichia coli, Is an Unusual GTPase with Circularly Permuted G-Motifs and Marked Burst Kinetics  Journal Articles
• [Population pharmacokinetics of two recombinant human coagulation factor Ⅷ preparations in patients with hemophilia A].  Journal Articles
• cDNA Cloning of PhosphoethanolamineN-Methyltransferase from Spinach by Complementation inSchizosaccharomyces pombe and Characterization of the Recombinant Enzyme  Journal Articles
• β-Catenin/CBP–Dependent Signaling Regulates TGF-β–Induced Epithelial to Mesenchymal Transition of Lens Epithelial Cells  Journal Articles
• γT‐S195A thrombin reduces the anticoagulant effects of dabigatran in vitro and in vivo  Journal Articles