Journal article
A Multicenter Study of Recombinant Factor VIII (RecombinateTM) in Previously Treated Patients with Hemophilia A
Abstract
A prospective, open-label multicenter investigation has been conducted to compare pharmacokinetic parameters of recombinant DNA-derived FVIII (rFVIII) and plasma-derived FVIII concentrate (pdFVIII) and to assess safety and efficacy of long-term home-treatment with rFVIII for subjects with hemophilia A. Following comparative in vivo pharmacokinetic studies, 69 patients with severe (n = 67) or moderate (n = 2) hemophilia A commenced a program of …
Authors
White GC; Courter S; Bray GL; Lee M; Gomperts ED
Journal
Thrombosis and Haemostasis, Vol. 77, No. 04, pp. 660–667
Publisher
Thieme
Publication Date
1997
DOI
10.1055/s-0038-1656030
ISSN
0340-6245